Pyridine-3-carboxamide derivatives

ABSTRACT

A compound of the formula (I)    &lt;IMAGE&gt;  (I)  or a salt thereof, wherein R is hydrogen atom, phenyl group which may be substituted freely or a group of -(CH2)n-R1 wherein n is an interger from 1 to 3 and R1 is hydrogen atom, hydroxy group, lower alkoxy group, mercapto group, lower alkylthio group, amino group, di-lower alkylamino group, C3-11 alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, 5- or 6-membered heterocyclic group, or phenyl group which may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy; R2 and R7 are different, hydrogen atom, C1-11 alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, lower alkoxyalkyl group, lower alkylthioalkyl group, phenyl group whch may be substiuted freely, aralkyl group whose nucleus may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy or haloalkyl gorup or 5- or 6-membered heterocyclic group; R3, R4 and R5 are, the same or different, hydrogen atom, halogen atom, cyano group, nitro group, amino group, lower alkyl group, lower haloalkyl group, hydroxy group, lower alkoxygroup, aryloxy group, carboxy group or lower alkoxycarbonyl group; R6 is hydrogen atom, halogen atom, lower alkyl group, phenyl group which may be substituted freely or aralkyl group which may be substituted freely; or R6 and R7 may be combined to form a group of -(CH2)m-(m is 3 or 4), which is useful e.g., a plant growth inhibitor.

BACKGROUND OF THE INVENTION

1. Field of the Invention

This invention relates to novel compounds which belong to 1,4-dihydro-4-oxo-3-pyridinecarboxamides. The compounds of this invention show growth inhibitory activities on plants and also antiinflammatory activity.

2. Description of the Prior Arts

Some compounds belonging to 1,4-dihydro-4-oxo-3-pyridinecarboxamides are found in literatures.

In Bull. Acad. Pol. Sci., Ser. Sci. Chim. 23(11), 901 (1975), Zankowska-Jasinska. W. et al., reported on N-(4-chlorophenyl)-1,4-dihydro-4-oxo-1,2,6-triphenyl-3-pyridinecarboxamide and 1-(4-chlorophenyl)-1,4-dihydro-4-oxo-N,2,6-triphenyl-3-pyridinecarboxamide. In Zesz. Nauk. Uniw. Jagiellon., Pr. Chim, 21., 141 (1976), Zankowska-Jasinska. W. et al., reported on 1,4-dihydro-4-oxo-N,2,6-triphenyl-3-pyridinecarboxamide, 1,4-dihydro-4-oxo-N,1,2,6-tetraphenyl-3-pyridinecarboxaminde, 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-diphenyl-3-pyridinecarboxamide.

In Yakugakuzassi, 101, 40 (1981), Kato et al. reported on four compounds, namely N-(4-clorophenyl)-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, 1,4-dihydro-2,6-dimethyl-4-oxo-N-phenyl-1-(phenylmethyl)-3-pyridinecarboxamide, 1,4-dihydro-N-(4-methoxyphenyl)-2,6-dimethyl-4-oxo-1-(phenylmethyl)-3-pyridinecarboxamide and N-(4-chlorophenyl)-1,4-dihydro-2,6-dimethyl-4-oxo-1-(phenylmethyl)-3-pyridinecarboxamide, as one of the studies on reactivity of ketene derivatives but they did not refer to utility thereof. Canadian Patent No. 1,115,278 [and also J. B. Pierce et al, J. Med. Chem. 25, 131 (1982)], there are disclosed 4-pyridone compounds possessing antiinflammatory activity, i.e., 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-diphenyl-3-pyridinecarboxamide, N,1-dibutyl-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, N,1-didodecyl-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, N-(4-chlorophenyl)-1-ethyl-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide, etc.

Cephalosporins which contain a partial structure of 1,4-dihydro-4-oxo-3-pyridinecarboxamide are known as medicine in Japanese Patent Unexamined Publication Nos. Sho 54(1979)-24892, Sho 51(1976)-43783 and Sho 51(1976)-48686.

On the other hand, 1,4-dihydro-4-oxo-3-pyridine-carboxylic acid derivatives as compounds which show plant growth regulating activity, especially chemical hybridizing activity, are known in Japanese Patent Unexamined Publication Nos. Sho 52(1977)-144,676 (see also U.S. Pat. No. 4,051,142) and Sho 57(1982)-114,573 (see also E.P. 40,082). However, plant growth inhibitory agents whose active ingredients are 1,4-dihydro-4-oxo-3-pyridinecarboxamide as in the formula (I) shown below are not known.

SUMMARY OF THE INVENTION

This invention provides compounds of the formula (I) and salts thereof. ##STR2## or a salt thereof wherein R is hydrogen atom, phenyl group which may be substituted freely or a group of --(CH₂)_(n) --R₁ wherein n is an integer from 1 to 3 and R₁ is hydrogen atom, hydroxy group, lower alkoxy group, mercapto group, lower alkylthio group, amino group, di-lower alkylamino group, C₃₋₁₁ alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, 5- or 6-membered heterocyclic group, or phenyl group which may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy; R₂ and R₇ are different, hydrogen atom, C₁₋₁₁ alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, lower alkoxyalkyl group, lower alkylthioalkyl group, phenyl group which may be substituted freely, aralkyl group whose nucleus may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy or haloalkyl group or 5-or 6-membered heterocyclic group;

R₃, R₄ and R₅ are, the same of different, hydrogen atom, halogen atom, cyano group, nitro group, amino group, lower alkyl group, lower haloalkyl group, hydroxy group, lower alkoxy group, aryloxy group, carboxy group or lower alkoxycarbonyl group;

R₆ is hydrogen atom, halogen atom, lower alkyl group, phenyl group which may be substituted freely or aralkyl group which may be substituted freely; or R₆ and R₇ may be combined to form a group of --(CH₂)_(m) --(m is 3 or 4).

This invention also provides plant growth inhibitors which contain at least one kind of compounds of the formula (I) and salts thereof as active ingredient.

DESCRIPTION OF PREFERRED EMBODIMENTS

The term of "lower" used for lower alkyl, lower alkoxy or like group in this invention means a group containing 1-5 carbon atoms. Specifically, there may be mentioned as lower alkyl group methyl, ethyl, propyl, isopropyl, butyl, isobutyl, pentyl or isopentyl; as lower alkoxy group methoxy, ethoxy, propoxy, isopropoxy or butoxy; as lower alkoxycarbonyl group methoxycarbonyl, ethoxycarbonyl, propoxycarbonyl or butoxycarbonyl; or as lower alkylthio group methylthio, ethylthio, propylthio, isopropylthio, butylthio or pentylthio. As lower alkenyl or lower alkynyl group may be mentioned vinyl, allyl, isopropenyl 2-butenyl, 1,3-butadienyl, 2-pentenyl, 1,4-pentadienyl, 1,6-heptadienyl, 1-hexenyl, ethynyl or 2-propynyl.

Examples of cycloalkyl group include cyclopropyl, cyclopentyl and cyclohexyl.

Examples of haloalkyl group include trifluoromethyl, chloromethyl and the like.

Examples of lower alkoxyalkyl group include methoxymethyl, ethoxymethyl, propoxymethyl, butoxymethyl and the like.

Examples of lower alkylthioalkyl group include methylthiomethyl, ethylthiomethyl, methylthioethyl, ethylthioethyl and the like.

Halogen atom includes chlorine, bromine, fluorine and iodine atom.

Examples of aralkyl group include benzyl, 3-phenylpropyl, 4-phenylbutyl and the like.

Examples of aryloxy group include phenyloxy, naphtyloxy and the like.

5- or 6-Membered heterocyclic group includes 5- or 6-membered one containing one to three hetero atoms selected from nitrogen atom, oxygen atom and sulfur atom. The examples of the 5-membered heterocyclic group are furyl, tetrahydrofuryl, thienyl, thiazolyl, isothiazolyl, oxazolyl, isooxazolyl or pyrazolyl and the 6-membered heterocyclic group are pyridyl, pyrimidinyl, pyrazinyl or pyridazinyl. These heterocyclic groups may be substituted by alkyl as methyl or ethyl, halogen atom or phenyl. When the heterocyclic group is substituted by phenyl, it may form a condensed ring combining the two adjacent carbon atoms in the heterocyclic group with phenyl group. Examples of the condensed ring are benzothiazolyl, benzofuryl, quinazolinyl or quinoxalinyl group.

Examples of substituent of phenyl group and aralkyl group which may be substituted freely include halogen atom, lower alkyl, lower alkoxy, trihaloalkyl, nitro, cyano and the like, and as numbers of the substituents one or two is preferable.

The compound of the formula (I) in this invention may form an addition salt with an acid such as hydrochloric acid, sulfuric acid, phosphoric acid, methanesulfonic acid, p-toluenesulfonic acid or trifluoroacetic acid when sufficiently basic, and also form a salt with an inorganic base when it contains a carboxylic group. Such salts are also included in this invention.

The compound of the formula (I) in this invention may be prepared by any of the following methods.

(Method A) ##STR3## [R, R₂, R₃, R₄ and R₅ of the formula (II) are the same as those in the formula (I)]

This method comprises reacting a 3-aminoacrylic acid anilide derivative (II) or its tautomer with 2,2,6-trimethyl-4H-1,3-dioxin-4-one in an appropriate solvent (e.g., toluene or xylene) under heating at a temperature of e.g., 100°-140° C. 2-Ethyl-2,6-dimethyl-4H-1,3-dioxin-4-one is also useful in place of 2,2,6-trimethyl-4H-1,3-dioxin-4-one. Also, in this method, 3-aminoacrylic acid anilide derivative (II) is not necessarily required to be in its isolated form but may be in the form of the crude reaction mixture of an amine of the formula (III) with a compound of the formula (IV) ##STR4## [R, R₂, R₃, R₄ and R₅ in the formula (III) and (IV) are the same as those in the formula (I).]

For the practical purpose it is convenient to use the crude reaction mixture as such

(Method B) ##STR5## [R, R₂, R₃, R₄, R₅, R₆ and R₇ in the formula (III) and (V) are the same as those in the formula (I).]

This method comprises reacting a 4-pyrone compound (V) corresponding to the formula (I), i.e., 4-oxo-N-phenyl-4H-pyran-3-carboxamide with ammonia or an amine of the formula (III) or a salt thereof in an appropriate solvent (e.g., ethanol or water) at a temperature from room temperature to about 60° C. The amount of ammonia or the amine employed is equimolecular or more to the 4-pyrone compound or a large excess if needed. When the amine is used as its available salt, it is required to convert to its free form by addition of an organic or an inorganic base in an amount needed for neutralization or more.

(Method C) ##STR6## [R, R₂, R₃, R₄, R₅, R₆ and R₇ in the formula (VI) and (VII) are the same meaning as defined in the formula (I).]

This method comprises reacting a carboxylic acid corresponding to the formula (I), i.e., 1,4-dihydro-4oxo-3-pyridinecarboxylic acid derivative (VI) with an aniline derivative (VII) in the presence of a condensing agent for dehydration. It is advantageous to use as the condensing agent for dehydration 1-substituted-2-halopyridinium salt and a tertiary amine according to the method described in e.g., Japanese Patent Unexamined Publication No. Sho 52(1977)-57,102. (Method C') ##STR7## [R, R₂, R₃, R₄, R₅, R₆ and R₇ in the formula (VIII) and (VII) are the same meaning as defined in the formula (I), and X is halogen atom.]

This method comprises reacting an acid halide (VIII) prepared easily by the reaction of (VI) and halogenating agent such as thionyl chloride with an aniline derivative (VII) in the presence of a base.

(Method D) ##STR8## [R, R₂, R₃, R₄, R₅ and R₇ of the formula (IX) are the same as those in the formula (I).]

This method comprises reacting a 1,4-dihydro-4-oxo-3-pyridinecarboxamide derivative (IX) with a halogenating reagent. It is especially advantageous to use as the halogenating reagent, N-chlorosuccinimide or N-bromosuccinimide in an appropriate chlorinated hydrocarbon solvent (e.g., dichloromethane, chloroform, tetrachloromethane, trichloroethylene or tetrachloroethane) in the presence or absence of free-radical initiator.

The reaction may be also conducted by dissolving the compound (IX) in a halogenated hydrocarbon as mentioned above, and blowing or dropping into the resultant solution bromine or chlorine in gaseous or liquid state.

In the above halogenation of the compound (IX), it may additionally give the substitution at phenyl group which is bonded at the amide nitrogen atom.

(Method E)

This method in conducted by treating a compound of the formula (I) (R₆ is halogen atom) with an alkali metal halide which concerns an exchange of halogen atom (R₆) in the formula (I). It is useful to synthesize a compound of the formula (I) in which R₆ is fluorine atom and which it is difficult to produce by direct introduction.

(Method F) ##STR9## [R, R₂, R₃, R₄, R₅, R₆ and R₇ in the formula (II), (X), (XI) and (XII) are the same as those in the formula (I).]

This method comprises reacting an 3-aminoacrylic acid anilide derivative (II) with acid halide (X) in the presence of a base to yield a compound of the formula (XI), and then reacting this compound (XI) with a N,N-dimethylamide dimethylketal derivative (XII). It is possible to use an ester of formic acid instead of (XII) in the case that R₇ is hydrogen atom. This method is useful to synthesize a compound of the formula (I) in which R₆ is aryl group.

For herbicidal applications, the compounds of the present invention are generally formulated into herbicidal compositions. These compositions can be solids such as dusts, granules, or wettable powders; or they can be liquids such as solutions, aerosols, or emulsifiable concentrates.

For example, solid compositions such as dusts, wettable powders or granules can be prepared by blending the active compound with a solid inert carrier such as the kaolinites, bentonites, clays, talcs, silicas and the like. Liquids compositions such as solutions or emulsifiable concentrates can be prepared by dissolving the active compound with a liquid inert solvent such as xylene, ethanol, acetone, dimethylformamide, some vegetable oils, water and so on.

Surface active agents for wetting, dispersing or emulsifying are generally used with the herbicidal compositions as above defined. For example; polyoxyethylene-alkyl ethers, polyoxyethylene-sorbitan fatty acid esters, and other nonionic types; alkyl and alkylarlyl sulfonates and sulfates and their sodium salts and other anionic types or other types of surface active agents.

For pre-emergence applications these herbicidal compositions are usually applied either as sprays, dusts, or granules in the area in which suppression of vegetation is desied. For post-emergence applications control of established plant growth, sprays or dusts are most commonly used. These formulations may contain 10-80% for wettable powders, 1-10% for granules, or 10-50% for emulsifiable concentrates by weight of active ingredient. Dosage of these herbicidal compositions for pre-emergence or postemergence applications is generally 0.1-2 Kg by weight of active ingredient.

This invention is illustrated further by examples hereinafter. Also, growth-inhibitory activities on plants of the compounds of the invention are shown in reference examples.

Furthermore, related specific compounds in addition to the compounds shown in the examples are as follows;

1. 1-butyl-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

2. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide

3. 2-ethyl-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

4. 1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

5. 1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

6. 2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

7. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

8. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

9. 2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

10. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-propyl-3-pyridinecarboxamide,

11. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide

12. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

13. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

14. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

15. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

16. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

17. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

18. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

19. 1,2-dibutyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide

20. 2-butyl-1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide

21. 2-butyl-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

22. 2-butyl-1-(4-chlorophenylmetyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

23. 2-butyl-cyclohexylmetyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

24. 2-butyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

25. 2-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

26. 2-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

27. 2-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

28. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-pentyl-3-pyridinecarboxamide,

29. 1-butyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl)-3-pyridinecarboxamide,

30. 1-hexyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl)-3-pyridinecarboxamide,

31. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

32. 1-(4-chlorophenylmethyl0-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

33. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

34. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

35. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

36. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

37. 1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

38. 1-butyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide

39. 1,4-dihydro-6-methyl-4-oxo-1,2-dipentyl-N-phenyl-3-pyridinecarboxamide,

40. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide

41. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

42. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

43. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

44. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

45. 1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

46. 1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

47. 1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

48. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N,2-diphenyl-3pyridinecarboxamide,

49. 1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

50. 1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

51. 1-butyl-2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

52. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide,

53. 2-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

54. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-phenylmethyl-3-pyridinecarboxamide,

55. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl3-pyridinecarboxamide,

56. 2-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

57. 2-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

58. 2-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

59. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

60. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

61. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

62. 2-(3-chlorophenyl)-1-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

64. 2-(3-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

65. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

66. 2-(3-chlorophenyl)-1-(4chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

67. 2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

68. 2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

69. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

70. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

71. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

72. 1-butyl-1,4-dihydro-6-methyl-2-(2-methyphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

73. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide,

74. 1-hexyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

75. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-furylmethyl-3-pyridinecarboxamide,

76. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

77. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

78. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

79. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

80. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

81. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

82. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

83. 1-butyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

84. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide,

85. 1-hexyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

86. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-phenylmethyl-3-pyridinecarboxamide,

87. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

88. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-3-pyridinecarboxamide,

89. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

90. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

91. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

92. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

93. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

95. 2-(2-furyl)-1,4-dihydro-6-4-oxo-1-pentyl-N-phenyl-3-pyridinecarboxamide,

96. 1-hexyl-2-(2furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

97. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

98. 1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

99. 1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

100. 2-(2-furyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

101. 2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

102. 2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

103. 2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

104. 1-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide,

105. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide,

106. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide,

107. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide,

108. 1,4- dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide,

109. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide,

110. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide,

111. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-3-pyridinecarboxamide,

112. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

113. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

114. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(2-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

115. 1-butyl-1,4-dihydro-6-methyl4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

116. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

117. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridine-carboxamide,

118. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-(phenylmethyl)-2-(3-pyridyl)-3-pyridinecarboxamide,

119. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

120. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

121. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

122. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

123. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

124. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

125. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(3-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

126. 1-butyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

127. 1,4-dihydro-6-methyl-4-oxo-1-pentyl-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

128. 1-hexyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

129. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-1-phenylmethyl-2-(4-pyridyl)-3-pyridinecarboxamide,

130. 1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

131. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

132. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3- pyridinecarboxamide,3-pyridinecarboxamide,

133. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

134. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

135. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

136. 1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-(4-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

137. 1-butyl-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

138. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

139. 2-ethyl-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

140. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

141. 2-ethyl-1,4- dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

142. 1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

143. 1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

144. 2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

145. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

146. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

147. 2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

148. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

149. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-propyl-3-pyridinecarboxamide,

150. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

151. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

152. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

153. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

154. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

155. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

156. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

157. 1,2-dibutyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

158. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-propyl-3-pyridinecarboxamide,

159. 2-butyl-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

160. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

161. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

162. 2-butyl-1-(4-methylphenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

163. 2-butyl-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

164. 2-butyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

165. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

166. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

167. 2-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

168. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

169. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-1-pentyl-4-oxo-3-pyridinecarboxamide,

170. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

171. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

172. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

173. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

174. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

175. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

176. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

177. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

178. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(2-methylpropyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

179. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

180. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1,2-dipentyl-3-pyridinecarboxamide,

181. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

182. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-phenylmethyl-3-pyridinecarboxamide,

183. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

184. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

185. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

186. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

187. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

188. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

189. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-pentyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

190. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-phenyl-3-pyridinecarboxamide,

191. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

192. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

193. 1cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

194. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

195. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

196. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

197. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

198. 1-butyl-2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

199. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

200. 2-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

201. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

202. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

203. 2-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

204. 2-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

205. 2-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

206. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

207. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

208. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

209. 1-butyl-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

210. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

211. 2-(3-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

212. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

213. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

214. 2-(3-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

215. 2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

216. 2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

217. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

218. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

219. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

220. 1-butyl-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

221. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

222. 1-hexyl-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

223. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

224. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

225. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

226. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

227. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

228. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

229. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

230. 1,4-dihydro-6-methyl-N,2-bis(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

231. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

232. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

233. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

234. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

235. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

236. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

237. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

238. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

239. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

240. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

241. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

242. 1-butyl-2(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

243. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

244. 2-(2-furyl)-1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

245. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

246. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

247. 1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

248. 1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

249. 2-(2-furyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

250. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

251. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

252. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

253. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

254. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-(2-pyridyl)-3-pyridinecarboxamide,

255. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

256. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide,

257. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

258. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

259. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

260. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

261. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

262. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

263. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

264. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

265. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-(3-pyridyl)-3-pyridinecarboxamide,

266. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

267. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-(3-pyridyl)-3-pyridinecarboxamide,

268. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

269. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

270. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

271. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

272. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

273. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

274. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(3-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

275. 1-butyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

276. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-pentyl-2-(4-pyridyl)-3-pyridinecarboxamide,

277. 1-hexyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

278. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-(4-pyridyl)-3-pyridinecarboxamide,

279. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

280. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

281. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

282. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

283. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

284. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

285. 1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

286. 1-butyl-N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

287. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl4-oxo-1-pentyl-3-pyridinecarboxamide,

288. N-(2-chlorophenyl)-2-ethyl-1-hexyl-1,4-dihydro-6-methyl4-oxo-3-pyridinecarboxamide,

289. N-(2-chlorophenyl)-2-ehtyl-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

290. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

291. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

292. N-(2-chlorophenyl)-1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

293. N-(2-chlorophenyl)-2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

294. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

295. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

296. N-(2-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

297. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

298. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-propyl-3-pyridinecarboxamide,

299. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

300. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide,

301. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

302. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

303. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

304. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

305. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

306. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

307. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

308. 1,2-dibuyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

309. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

310. 2-butyl-N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

311. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

312. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

313. 2-butyl-N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

314. 2-butyl-N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

315. 2-butyl-N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

316. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

317. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

318. 2-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

319. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

320. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

321. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

322. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

323. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

324. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

325. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

326. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

327. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

328. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

329. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylpropyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

330. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide,

331. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1,2-dipentyl-3-pyridinecarboxamide,

332. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide,

333. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-phenylmethyl-3-pyridinecarboxamide,

334. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

335. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide,

336. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide,

337. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide,

338. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

339. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

340. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

341. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-phenyl-3-pyridinecarboxamide,

342. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

343. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-phenylmethyl3-pyridinecarboxamide,

344. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

345. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

346. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

347. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

348. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

349. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

350. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

351. 1-butyl-N,2-bis(2-chlorophenyl)1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

352. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

353. N,2-bis(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

354. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

355. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

356. N,2-bis(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

357. N,2-bis(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

358. N,2-bis(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

359. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

360. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

361. N,2-bis(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

362. 1-butyl-N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

363. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

364. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

365. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

366. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

367. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

368. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

369. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

370. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

371. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

372. N-(2-chlorophenyl)-2-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

373. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

374. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

375. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

376. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

377. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

378. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

379. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

380. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

381. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

382. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

383. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

384. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

385. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

386. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

387. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

388. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

389. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

390. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

391. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

392. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

393. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

394. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

395. 1-butyl-N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

396. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide, 397. N-(2-chlorophenyl)-2-(2-furyl)-1-hexyl-1,4-dihydro-6-methyl-4oxo--3-pyridinecarboxamide,

398. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

399. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

400. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

401. N-(2-chlorophenyl)-1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

402. N-(2-chlorophenyl)-2-(2-furyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

403. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

404. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

405. N-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

406. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

407. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4oxo-1-pentyl-2-(2-pyridyl)-3-pyridinecarboxamide,

408. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

409. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide,

410. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

411. N-(2-chlorophenyl)-1-(4chlorophenylmethyl)-1,4-dihydro-6methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

412. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

413. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

414. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

415. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

416. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

417. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

418. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-(3-pyridyl)-3-pyridinecarboxamide,

419. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

420. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-(3-pyridyl)-3-pyridinecarboxamide,

421. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

422. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

423. N-(2-chlorophenyl)-1-cyclohexymethyl-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

424. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

425. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

426. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

427. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

428. 1-butyl-N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

429. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-2-(4-pyridyl)-3-pyridinecarboxamide,

430. N-(2-chlorophenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

431. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenylmethyl-2-(4-pyridyl)-3-pyridinecarboxamide,

432. N-(2-chlorophenyl)-1.4-dihydro-6-methyl-1-(4-methylphenylmethyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

433. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

434. N-(2-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

435. N-(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

436. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

437. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

438. N-(2-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

439. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

440. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-methylphenylmethyl)-3-pyridinecarboxamide,

441. 1-(4-chlorophenylmethyl)-2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

442. 1-cyclohexylmethyl-2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl-4-oxo-3-pyridinecarboxamide,

443. 2-ethyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

444. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

445. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

446. 2-ethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

447. 1,4-dihydro-6methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide,

448. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

449. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

450. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

451. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

452. 1,4-dihydro-6-methyl-N-(2,3-dimethylpheny;)-4-oxo-2-propyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

453. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

454. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-propyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

455. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

456. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

457. 2-butyl-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

458. 2-butyl-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

459. 2-butyl-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

460. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

461. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

462. 2-butyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

463. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

464. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

465. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

466. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

467. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-3-pyridinecarboxamide,

468. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

469. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

470. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-2-(2-methylpropyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

471. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-phenylmethyl-3-pyridinecarboxamide,

472. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

473. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

474. 1-cyclohexymethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

475. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-3-pyridinecarboxamide,

476. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

477. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

478. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-pentyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

479. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

480. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

481. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

482. 1-(2-furylmethyl)1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

483. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridylmethyl)-3-pyridinecarboxamide,

484. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

485. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-phenyl-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

486. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

487. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

488. 2-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

489. 2-(2-chlorophenyl)-1-cyclohexymethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

490. 2(2-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

491. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

492. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

493. 2-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

494. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

495. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

496. 2-(3-chlorophenyl)-1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

497. 2-(3-chlorophenyl)-1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

498. 2-(3-chlorophenyl)-1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

499. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

500. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

501. 2-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

502. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

503. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

504. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

505. 1cyclohexylmethyl-1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

506. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

507. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

508. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

509. 1,4-dihydro-6-methyl-2-(2-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-pyridelmethyl)-3-pyridinecarboxamide,

510. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

511. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-1(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

512. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

513. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-2(3-methylphenyl)-N-(2,3-dimethylmethyl)-4-oxo-3-pyridinecarboxamide,

514. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

515 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethyplhenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

516. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

517. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

518. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

519. 2-(2furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

520. 1-(4-chlorophenylmethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

521. 1-cyclohexylmethyl-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

522. 2-(2-furyl)-1-(2furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

523. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

524. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

525. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

526. 1,4-dihydro-6-methyl-N-(s,3-dimethylphenyl)-4-oxo-1-phenylmethyl-2-(2-pyridyl)-3-pyridinecarboxamide,

527. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

528. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

529. 1-cylcohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)--4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

530. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

531. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

532. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

533. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(2ppyridyl)-1-(4-pyridylmethyl)-3-pyridinecarboxamide,

534. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenylmethyl-2-(3-pyridyl)-3-pyridinecarboxamide,

535. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)1-(4methylphenylmethyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

536. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3ppyridyl)-3-pyridinecarboxamide,

537. 1-cyclohexymethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

538. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

539. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

540. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(3-pyridyl)-1-(3-pyridylmethyl)-3-pyridinecarboxamide,

541. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridylmethyl)-3-pyridinecarboxamide,

542. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

543. 1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-1(4-methylphenylmethyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

544. 1-(4-chlorophenylmethyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

545. 1-cyclohexylmethyl-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

546. 1-(2-furylmethyl)-1,4-dihydro-6-methyl-N-(2,3dimethylphenyl)-4-oxo-2-(4-puridyl)-3-pyridinecarboxamide,

547. 1,4dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-1-(2-pyridylmethyl)-3-pyridinecarboxamide,

548. 1,4dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-1(3-pyridylmethyl)-3-pyridinecarboxamide,

549. 1,4dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-2-(4-pyridyl)-1(4-pyridylmethyl)-3-pyridinecarboxamide,

550. 1-butyl-2-ethyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

551. 2-ethyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

552. 2-ethyl-1-hexyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)4-oxo-3-pyridinecarboxamide,

553. 2-ethyl-1,4dihydro-1(3-methoxypropyl)-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

554. 2-ethyl-1,4dihydro-1-(2-methoxyethyl)-6-methyl-N-(2,6dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

555. 1-(ethoxyethyl)-2-ethyl-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

556. 1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1,2-diphenyl-3-pyridinecarboxamide,

557. 1-(2-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

558. 1-(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

559. 1-(4-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

660. 1,4dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

561. 1,4dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

562. 1,4dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

563. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6 -dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

564. 1,2-bis(2-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

565. 2-(2-chlorophenyl)-1(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

566. 2-(2-chlorophenyl)-1-(4-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

567. 2-(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

568. 1-(2-chlorophenyl)-2(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

569. 2-(2-chlorophenyl)-1(3-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

570. 2-(3-chlorophenyl)-1-(4-chlorophenyl)-1,4dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

571. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

572. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

573. 2-(2-chlorophenyl)-1,4dihydro-6-methyl-1(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

574. 2-(3-chlorophenyl)-1,4dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

575. 2-(3-chlorophenyl)-8-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

576. 2-(3-chlorophenyl)-1,4dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

577. 1,4dihydro-6-methyl-2(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

578. 1-(2-chlorophenyl)-1,4dihydro-6-methyl-2-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

579. 1-(3-chlorophenyl)-1,4dihydro-6-methyl-2-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

580. 1-(4-chlorophenyl)-1,4dihydro-6-methyl-2-(2-methylphenyl)-N-(2,6-dimethylphenyl)-6-oxo-3-pyridinecarboxamide,

581. 1,4dihydro-6-methyl-1,2-bis(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

582. 1,4dihydro-6-methyl-2-(2-methylphenyl)-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

583. 1,4dihydro-6-methyl-2-(2-methylphenyl)-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

584. 1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

585. 1-(1-chlorophenyl)-1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

586. 1-(3-chlorophenyl)-1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

587. 1-(4-chlorophenyl)-1,4dihydro-6-methyl-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

588. 1,4-dihydro-6-methyl-1-(2-methylphenyl)-2-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4oxo-3-pyridinecarboxamide,

589. 1,4-dihydro-6-methyl-1,2-bis(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

590. 1,4-dihydro-6-methyl-2-(3-methylphenyl)-1(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

591. 2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,3-dimethylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

592. 1-(2-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

593. 1-(3-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

594. 1-(4-chlorophenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)4-oxo-3-pyridinecarboxamide,

595. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

596. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

597. 2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

598. 1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-(2-pyridyl)-3-pyridinecarboxamide,

599. 1-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

600. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

601. 1-(4-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

602. 1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

603. 1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-pyridyl)-3-pyridinecarboxamide,

604. 1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

605. 1,4-dihydro-6-methyl-N-(2,6-dimethyphenyl)-4-oxo-1-phenyl-2(3-pyridyl)-3-pyridinecarboxamide,

606. 1-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

607. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2(3-pyridyl)-3-pyridinecarboxamide,

608. 1-(4-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

609.1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

610. 1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

611. 1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

612. 1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenyl-2(4-pyridyl)-3-pyridinecarboxamide,

613. 1-(2-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pryridyl)-3-pyridinecarboxamide,

614. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

615. 1-(4-chlorophenyl)-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

616. 1,4-dihydro-6-methyl-1-(2-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

617. 1,4-dihydro-6-methyl-1-(3-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

618. 1,4-dihydro-6-methyl-1-(4-methylphenyl)-N-(2,6-dimethylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

619. 5-bromo-1-butyl-2-ethyl-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-44-oxo-3-pyridinecarboxamide,

620. 5-bromo-2-ethyl-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

621. 5-bromo-2-ethyl-1-hexyl-1,4-dihydro-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

622. 5-bromo-2-ethyl-1,4-dihydro-1-(3-methoxypropyl)-6-methyl-N-(2,6-dimethylphenyl)-4oxo-3-pyridinecarboxamide,

623. 5-bromo-2-ethyl-1,4-dihydro-1(2-methoxyethyl)-6-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

624. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

625. 2-ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

626. 5-bromo-2-ethyl-N-(2,6-diethylmethyl)-1,4-dihydro-1-(2-methoxyethyl)-6-methyl-4-oxo-3-pyridinecarboxamide,

627. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1-(3-methoxypropyl)-6-methyl-4-oxo-3-pyridinecarboxamide,

628. 2ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1-(2-methoxyethyl)-6-methyl-4-oxo-3-pyridinecarboxamide,

629. 1-(2-ethoxyethyl)-2ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

630. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

631. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

632. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

6.33 N-(2,6diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2phenyl-3-pyridinecarboxamide,

634. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(4-methylphenyl)-4-2phenyl-3-pyridinecarboxamide,

635. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide,

636. 1,2-bis(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

637. 2-(2-chlorophenyl)-1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

638. 2-(2-chlorophenyl)-1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

639. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

640. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

641. 2-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

642. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide,

643. 1-(2-chlorophenyl)-2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

644. 1,2-bis(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

645. 2-(3-chlorophenyl)-1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

646. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

647. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

648. 2-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

649. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

650. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

651. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

652. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

653. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

654. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

655. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

656. N-(2,6-diethylphenyl)-1,4-dihydro-6methyl-2-(3-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

657. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

658. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

659. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

660. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

661. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1,2-bis(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

662. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-2-(4-methylphenyl)-4-oxo- 3-pyridinecarboxamide,

663. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

664. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

665. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4oxo-3-pyridinecarboxamide,

666. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-2-(2-furyl)-8,6-methyl-4-oxo-3-pyridinecarboxamide,

667. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

668. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

669. N-(2,6-diethylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

670. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2(2-pyridyl)-3-pyridinecarboxamide,

671. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

672. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

673. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

674. N-(2,6-diethelphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

675. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(3-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

676. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2(2pyridyl)-3-pyridinecarboxamide,

677. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

678. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

679. 1(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

680. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

681. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-2(3-pyridyl)-3-pyridinecarboxamide,

682. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2(3-pyridyl)-3-pyridinecarboxamide,

683. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

684. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

685. 1-(2-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

686. 1-(3-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

687. 1-(4-chlorophenyl)-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

688. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

689. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

690. N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

691. 5-bromo-1-(2-ethoxyethyl)-2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

692. 5-bromo-2-ethyl-N-(2,6-diethelphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

693. 5-bromo-2-ethyl-N-(2,6-diethylphenyl)-1-hesyl-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

694. 5-bromo-2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

695. 1-butyl-2-ethyl-Np(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

696. 2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

697. 2-ethyl-N-(2-ethyl-6-methylphenyl)-1hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

698. 2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-1-(3-methoxypropyl)-6-methyl-4-oxo-3-pyridinecarboxamide,

699. 2-ethyl-N-(2-ethyl-6methylphenyl)-1,4-dihydro-1(2-methoxyethyl)-6-methyl-4-oxo-3-pyridinecarboxamide,

700. 1-(2-ethoxyethyl)-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

701. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-N,1-diphenyl-3-pyridinecarboxamide,

702. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

703. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

705. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

706. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

707. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

708. 2-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide,

709. 1,2-bis(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

710. 2-(2-chlorophenyl)-1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

711. 2-(2-chlorophenyl)-1(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

712. 2-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

713. 2(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

714. 2-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

715. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide,

716. 1-(2-chlorophenyl)-2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

717. 1,2-bis(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

718. 2-(3-chlorophenyl)-1-(4-chlorophenyl)-N-(2ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

719. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

720. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-=b 6-methyl-1(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

721. 2-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

722. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

723. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl-4-oxo-3-pyridinecarboxamide,

724. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

725. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

726. N-(2-ethyl-6-methylphenyl)-8,6-methyl-1,2-bis(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

727. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(3-methylphenyl)4-oxo-3-pyridinecarboxamide,

728. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2(2-methylphenyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

729. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6methyl-2(3-methylphenyl)-4-oxo-1-phenyl-3-pyridinecarboxamide,

730. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

731. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

732. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)1,4-dihydro-6-methyl-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

733. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-2-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

734. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1,2-bis(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

735. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-2-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

736. N-(2-ethyl-6methylphenyl)-2(2-furyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-3-pyridinecarboxamide,

737. 1(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-0x0-3-pyridinecarboxamide,

738. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

739. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-2-(2-furyl)1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

740. N-(2-ethyl-6methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl)-1-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

741. N-(2-ethyl-6-methylphenyl)-2(2-furyl)-1,4-dihydro-6-methyl)-1-(3-methylphenyl)-4-oxo-3-pyridinecarboxamide,

742. N-(2-ethyl-6-methylphenyl)-2-(2-furyl)-1,4-dihydro-6-methyl)-1-(4-methylphenyl)-4-oxo-3-pyridinecarboxamide,

743. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-(2-pyridyl)-3-pyridinecarboxamide,

744. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

745. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

746. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

747. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(2-methylphenyl)-4-oxo-2(2-pyridyl)-3-pyridinecarboxamide,

748. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(3-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

749. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(4-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

750. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(3-pyridyl)-3-pyridinecarboxamide,

751. 1-(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

752. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

753. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(3-pridyl)-3-pyridinecarboxamide,

754. N-(2-ethyl-6-methelphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-(2-pyridyl)-3-pyridinecarboxamide,

755. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

756. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1(4-methylphenyl)-4-oxo-2-(3-pyridyl)-3-pyridinecarboxamide,

757. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-phenyl-2-(4-pyridyl)-3-pyridinecarboxamide,

758. 1(2-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

759. 1-(3-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

760. 1-(4-chlorophenyl)-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

761. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(2-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

762. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-1-(3-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

763. N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6methyl-1-(4-methylphenyl)-4-oxo-2-(4-pyridyl)-3-pyridinecarboxamide,

764. 5-bromo-1-butyl-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

765. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-6-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

766. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)1-hexyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

767. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-1-(3-methoxypropyl)-6-methyl-4-oxo-3-pyridinecarboxamide,

768. 5-bromo-2-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-1-(2-methoxyethyl)-6-methyl-4oxo-3-pyridinecarboxamide,

769. 6-ethyl-1,4-dihydro-2-methyl-1(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

770. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-2-methyl-4oxo-N-phenyl-3-pyridinecarboxamide,

771. 1-cyclohexylmethyl-6-methyl-1,4-dihydro-2-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

772. 6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

773. 6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

774. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

775. 1-cyclohexylmethyl-6-ethyl-1,4-dihydro-2-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

776. N-(2-chlorophenyl)-6ethyl-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

777. N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-2-methyl-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

778. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

779. N-(2-chlorophenyl)-1-cyclohexylmethyl-6-ethyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

780. 6-ethyl-1,4-dihydro-4-oxo-N-phenyl-1-phenylmethyl-2-propyl-3-pyridinecarboxamide,

781. 6-ethyl-1,4-dihydro-1-(4-methylphenylmethyl)-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

782. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

783. 1-cyclohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

784. 6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide,

785. 6-ethyl-1,4-dihydro-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

786. 1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

787. 1cyclohexylmethyl-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

788. N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-4-oxo-1-phenylmethyl-2-propyl-3-pyridinecarboxamide,

789. N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-1-(4-methylphenylmethyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

790. N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-2-propyl-3-pyridinecarboxamide,

791. N-(2-chlorophenyl)-1-clorohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-2-propyl-3-pyridinecarboxamide,

792. 2-butyl-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-1-phenylmethyl-3-pyridinecarboxamide,

793. 2-butyl-6-ethyl-1,4-dihydro-1(4-methylphenylmethyl)-4-oxo-N-phenyl-3-pyridinecarboxamide,

794. 2-butyl-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-N--phenyl-3-pyridinecarboxamide,

795. 2-butyl-1-cyclohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-N-phenyl-3-pyridinecarboxamide,

796. 2-butyl-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

797/ 2-butyl-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-1-(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

798. 2-butyl-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

799. 2-butyl-1-cyclohexylmethyl-6ethyl-1,4-dihydro-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

800. 2-butyl-N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

801. 2-butyl-N-(2-chlorophenyl)-6-ethyl-1,4-dihydro-1(4-methylphenylmethyl)-4-oxo-3-pyridinecarboxamide,

802. 2-butyl-N-(2-chlorophenyl)-1-(4-chlorophenylmethyl)-6-ethyl-1,4-dihydro-4-oxo-3-pyridinecarboxamide,

803. 2-butyl-N-(2-chlorophenyl)-1-cyclohexylmethyl-6-ethyl-1,4-dihydro-4-oxo-3-pyridinecarboxamide,

804. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

805. 6-ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

806. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

807. 5-bromo-6-ethyl-N-(2,6diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

808. 5-bromo-6ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

809. 5-bromo-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

810. 1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide,

811. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

812. 6-ethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide,

813. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

814. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-(2-phenylmethyl)-3-pyridinecarboxamide,

815. 1-butyl-5,6-diethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

816. 5,6-diethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

817. 5,6-diethyl-N-(2,6-diethylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

818. 5,6-diethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

819. 5,6-diethyl-N-(2,6 -diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-(1-phenylmethyl)-3-pyridinecarboxamide,

820. 1-butyl-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

821. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

822. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

823. 6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

824. 6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1(2-phenylethyl)-3-pyridinecarboxamide,

825. 5-bromo-1-butyl-6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

826. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

827. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

838. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

829. 5-bromo-6-ethyl-N-(2-ethyl-6-methylphenyl)1,4-dihydro-2-methyl-4-oxo-1-(2-phenylethyl)-3-pyridinecarboxamide,

830. 1-butyl-6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide,

831. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

832. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1-hexyl-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide,

833. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

834. 6-ethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

835. 1-butyl-5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

836. 5,6-diethyl-N-(2-ethyl-6methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

837. 5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1-hexyl-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

838. 5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

839. 5,6-diethyl-N-(2-ethyl-6-methylphenyl)-1,4-dihydro-2-methyl-4-oxo-1-(2-phenylethyl)-3-pyridinecarboxamide,

840. 1-butyl-6-ethyl-N-(2,6-dimethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide,

841. 6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

842. 6-ethyl-1-hexyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

843. 6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

844. 6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1(2-phenylethyl)-3-pyridinecarboxamide,

845. 5-bromo-1-butyl-6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

846. 5-bromo-6-ethyl-1,4-dihydro-2methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

847. 5-bromo-6-ethyl-1-hexyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

848. 5-bromo-6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethelphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

849. 5-bromo-6-ethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-(2-phenylethyl)-3-pyridinecarboxamide,

850. 1-butyl-6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

851. 6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

852. 6-ethyl-1-hexyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

853. 6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

854. 6-ethyl-1,4-dihydro-2,5-dimethyl-N-(2,6-dimethylphenyl)-4-oxo-1(2-phenylethyl)-3-pyridinecarboxamide,

855. 1-butyl-5,6-diethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

856. 5,6-diethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-pentyl-3-pyridinecarboxamide,

857. 5,6-diethyl-1-hexyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-3-pyridinecarboxamide,

858. 5,6-diethyl-1,4-dihydro-2-methyl-N-(2,6-dimethylphenyl)-4-oxo-1-phenylmethyl-3-pyridinecarboxamide,

859. 5,6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

860. 5-ethyl-N-(2,6-diethylphenyl)-8,1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

861. N-(4-bromo-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

862. 2-butyl-5-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

863. 5-bromo-1-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

864. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-1-ethyl-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

865. 5-bromo-2-butyl-N-(2,6-diethylphenyl)-1-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

866. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-2-butyl-1-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

867. 1-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

868. N-(4-bromo-2,6-diethylphenyl)-1-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

869. 2-butyl-1-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide,

870. N-(4-bromo-2,6-diethylphenyl)-2-butyl-1-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide,

871. 5-bromo-N-(2,6-diethylphenyl)-6-ethyl-1,4-dihydro-1-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

872. 5-bromo-2-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1-methyl-4-oxo-3-pyridinecarboxamide,

873. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-6-ethyl-1,4-dihydro-1,2-dimethyl-4-oxo-3-pyridinecarboxamide,

874. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,5-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

875. N-(4-bromo-2,6-diethylphenyl)-6-ethyl-1,4-dihydro-1,5-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

876. 2-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-1,5-dimethyl-4-oxo-3-pyridinecarboxamide,

877. N-(4-bromo-2,6-diethylphenyl)-2-butyl-6-ethyl-1,4-dihydro-1,5-dimethyl-4-oxo-3-pyridinecarboxamide,

878. 5-chloro-N-(2,6diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

879. N-(4-bromo-2,6-diethylphenyl)5-chloro-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

880. 2-butyl-5-chloro-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

881. N-(4-bromo-2,6-diethylphenyl)-2-butyl-5-chloro-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

882. 5-bromo-N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

883. N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

884. 5-bromo-2-butyl-N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

885. 2-butyl-N-(4-chloro-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

886. 5-bromo-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

887. N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

888. 5-bromo-2-butyl-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

889. 2-butyl-N-(2,6-diethyl-4-methylphenyl)1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

890. N-(4-bromo-2,6-diethylphenyl)-2-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide,

891. N-(4-bromo-2,6-diethylphenyl)-6-methyl-1,4-dihydro-2,5-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide,

892. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide,

893. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-propyl-3-pyridinecarboxamide,

894. N-(4-bromo-2,6-diethylphenyl)-2-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

895. N-(4-bromo-2,6-diethylphenyl)-6-ethyl-1,4-dihydro-2,5-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

896. 2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

897. 6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-1-pentyl-3-pyridinecarboxamide,

898. N-(4-bromo-2,6-diethylphenyl)-1-butyl-2-ethyl-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide,

899. N-(4-bromo-2,6-diethylphenyl)-1-butyl-6-ethyl-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide,

900. 1-butyl-2-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-5,6-dimethyl-4-oxo-3-pyridinecarboxamide,

901. 1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,5-dimethyl-4-oxo-3-pyridinecarboxamide,

902. 1-(3-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

903. 1-(3-bromophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

904. 2-ethyl-1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

905. 2-ethyl-1,4-dihydro-1-(3-iodophenyl)-6-methyl-4oxo-N-phenyl-3-pyridinecarboxamide,

906. 2-ethyl-1-(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl4-oxo-N-phenyl-3-pyridinecarboxamide,

907. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

908. 1-(3-bromophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

909. 1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

910. 1,4-dihydro-1-(3-iodophenyl)-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

911. 1-(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-2-propyl-3-pyridinecarboxamide,

912. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl3-pyridinecarboxamide,

913. 1-(3-bromophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

914. 1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

915. 1,4-dihydro-1-(3-iodophenyl)-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

916. 1(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-N-phenyl-3-pyridinecarboxamide,

917. 2-butyl-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

918. 2-butyl-1(2,5-dichlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

919. 2-butyl-1(2,6-dichlorophenyl)1,4-dihydro-6-methyl-4-oxo-N-phenyl-3-pyridinecarboxamide,

920. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide,

921. 1-(3-bromophenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide,

922. 1-(3-fluorophenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide,

923. 1,4-dihydro-1-(3-iodophenyl)-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide,

924. 1-(3-trifluoromethylphenyl)-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide,

925. 1-(3-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

926. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-propyl-3-pyridinecarboxamide,

927. 2-butyl-1-(3-chloropheynl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-3-pyridinecarboxamide,

928. 1-(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo2-pentyl-3-pyridinecarboxamide,

929. 1(3-chlorophenyl)-1,4-dihydro-6-methyl-N-(2-methylphenyl)-4-oxo-2-phenyl-3-pyridinecarboxamide,

930. N-(2-chlorophenyl)-1-(3-chlorophenyl)-2-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

931. N-(2-chlorophenyl)-1(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-propyl-3-pyridinecarboxamide,

932. 2-butyl-N-(2-chlorophenyl)-1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxamide,

933. N-(2-chlorophenyl)-1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-pentyl-3-pyridinecarboxamide,

934. N-(2-chlorophenyl)-1-(3-chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-2-phenyl-3-pyridinecarboxamide,

935. 5-bromo-N-(2,6-diethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

936. 5-bromo-N-(2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

937. 5-bromo-N-(2,6-diethyl-4methylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

938. 5-bromo-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

939. 5-bromo-2-butyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

940. 5-bromo-N-(2,4,,6-triethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

941. 5-bromo-N-(2,4,6-triethylphenyl)-1,4-dihydro-1.6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

942. 5-bromo-N-(2,6-diethyl-4-propylphenyl)1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

943. 5bromo-2-butyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

944. 5-bromo-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

945. 5-bromo-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

946. 5-bromo-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

947. 5-bromo-2-butyl-N-(2,6-diethyl-4(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

948. 5-bromo-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-2-methoxymethyl-1,4-dimethyl-4-oxo-3-pyridinecarboxamide,

949. 5-bromo-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

950. 5-bromo-N-(2,6diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

951. 5-bromo-2-butyl-N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

952. 5bromo-N-(b 2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-2-methoxymethyl-1,6dimethyl-4-oxo-3-pyridinecarboxamide,

953. 5-bromo-N-(2,6-diethyl-4(1,1dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-2methylthiomethyl-4-oxo-3-pyridinecarboxamide,

954. 5-bromo-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

955. 5-bromo-2-butyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

956. 5-bromo-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

957. 5-bromo-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

958. 5-bromo-N-(4-bromo-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

959. 5-bromo-N-(bromo-2,6-diethylphenyl)-2-butyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

960. 5-bromo-2-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

961. 5-bromo-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

962. 5-bromo-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

963. 5-bromo-2-butyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

964. 5-bromo-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

965. 5-bromo-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl)-4-oxo-3-pyridinecarboxamide,

966. 5-bromo-2-butyl-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

967. 5-bromo-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

968. 5-bromo-N-(b 2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

969. 5-bromo-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

970. 5-bromo-2-butyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

971. 5-bromo-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-2-methoxyphenyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

972. 5-bromo-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

973. N-(4-amino-2,6-diethylphenyl)-5-bromo-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

974. N-(4-amino-2,6-diethylphenyl)-5-bromo-2-butyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

975. N-(4-amino-2,6-diethylphenyl)-5-bromo-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo3-pyridinecarboxamide,

976. N-(4-amino-2,6-diethylphenyl)-5-bromo-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

977. 5-bromo-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

978. 5-bromo-2-butyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

979. 5-bromo-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

980. 5-bromo-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4oxo-3-pyridinecarboxamide,

981. 5-bromo-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

982. 5-bromo-2-butyl-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

983. 5-bromo-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

984. 5-bromo-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

985. 5-bromo-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4oxo-2-propyl-3-pyridinecarboxamide,

986. 5-bromo-2-butyl-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

987. 5-bromo-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-2-methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

988. 5-bromo-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

989. 5-bromo-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

990. 5-bromo-2-butyl-N-(2,6-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

991. 5-bromo-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro--2methoxymethyl-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

992. 5-bromo-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-2-methylthiomethyl-4-oxo-3-pyridinecarboxamide,

993. 5-bromo-N-(2,6-diethyl-4-hydroxyphenyl)1,4-dihydro-1,6-dimethyl-4oxo-2-propyl-3-pyridinecarboxamide,

994. 2-butyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,5,6trimethyl-4-oxo-3-pyridinecarboxamide,

995. N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

996. 2-butyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

997. N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

998. 2-butyl-N-(2,6-diethyl-4-(1-methylethyl)phenyl)1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

999. N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1000. 2-butyl-N-(2,6-diethyl-4(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1001. N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1002. 2-butyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1003. 2-butyl-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1004. N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1005. 2-butyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1006. N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,5,6trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1007. 2-butyl-N-(2,6-dimethyl-4-methoxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1008.N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1009. 2-butyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1010. N-(4-amino-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1011. N-(4-amino-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1012. N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1013. 2-butyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1014. N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-[1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1015. 2-butyl-N-(4-cyano-2,6-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1016. N-(2,6-diethyl-4-diethylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1017. 2-butyl-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1018. N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1019. 2-butyl-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,5,6-trimethyl-4-oxo-3-pyridinecarboxamide,

1020. 5-ethyl-N-(2,6-diethyl-4-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1021. 2-butyl-5-ethyl-N-(2,6-diethyl-6-methylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1022. 5-ethyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1023. 2-butyl-5-ethyl-N-(2,4,6-triethylphenyl)-1,4-dihydro-1,6-dimethyl--oxo-3-pyridinecarboxamide,

1024. 5-ethyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1025. 2-butyl-5-ethyl-N-(2,6-diethyl-4-propylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1026. 5-ethyl-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1027. 2-butyl-5-ethyl-N-(2,6-diethyl-4-(1-methylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1028. 5-ethyl-N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1029. 2-butyl-5-ethyl-N-(2,6-diethyl-4-(1,1-dimethylethyl)phenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1030. 5-ethyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1031. 2-butyl-5-ethyl-N-(2,6-diethyl-4-trifluoromethylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1032. 5-ethyl-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1033. 2-butyl-5-ethyl-N-(2,6-diethyl-4-iodophenyl)-1,4-dihydro--1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1034. 5-ethyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1035. 2-butyl-5-ethyl-N-(2,6-diethyl-4-hydroxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1036. 5-ethyl-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1037. 2-butyl-5-ethyl-N-(2,6-diethyl-4-methoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1038. 5-ethyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1039. 2-butyl-5-ethyl-N-(2,6-diethyl-4-phenoxyphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1040. N-(4-amino-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1041. N-(4-amino-2,6-diethylphenyl)-2-butyl-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1042. 5-ethyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1043. 2-butyl-5-ethyl-N-(2,6-diethyl-4-nitrophenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1044. N-(4-amino-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1045. 2-butyl-N-(4-cyano-2,6-diethylphenyl)-5-ethyl-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

1046. 5-ethyl-n-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1047. 2-butyl-5-ethyl-N-(2,6-diethyl-4-methoxycarbonylphenyl)-1,4-dihydro-1,6dimethyl-4-oxo-3-pyridinecarboxamide,

1048. 5-ethyl-N-(2,6-diethyl-4ethoxycarbonylphenyl)-1,4-dihydro-1,6dimethyl-4-oxo-2-propyl-3-pyridinecarboxamide,

1049. 2-butyl-5-ethyl-N-(2,6-diethyl-4-ethoxycarbonylphenyl)-1,4-dihydro-1,6-dimethyl-4-oxo-3-pyridinecarboxamide,

EXAMPLE 1 1-butyl-1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-3-pyridinecarboxamide

A mixture of 4.42 g (18.47 mmol) of α-benzoylacetanilide, 1.89 g (25.84 mmol) of n-butylamine, one drop of acetic acid and 25 ml of toluene was refluxed for 1.5 hours, while the resulted water and excess of butylamine were removed through a Dean-Stark's water separator, together with about 12 ml of toluene. While heating, to the mixture was dropwise added a solution of 7.2 g (46.18 mmol) of 2-ethyl-2,6-dimethyl-4H-1,3-dioxin-4-one in 16 ml of toluene within about 30 minutes and after the resulted mixture was refluxed for forty minutes, it was cooled to room temperature. The crystals precipitated was separated by filtration and dried under vacuo to afford 3.72 g of the title compound having mp. 189.5°-193° C.

EXAMPLE 2 1,4-dihydro-6-methyl-4-oxo-N,2-diphenyl-1-pentyl-3-pyridinecarboxamide

1 g (3.23 mmol) of 6-methyl-4-oxo-N,2-diphenyl-4-H-pyran-3-carboxamide and 590 mg (6.78 mmol) of benzylamine were dissolved in 10 ml of ethanol, and the resulted mixture was stirred over night at room temperature. Ethanol was removed under vacuo. The crystal residue was recrystallized from ethylacetate to afford 700 mg of the title compound having mp. 164°-165.5° C.

EXAMPLE 3 5-bromo-1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide

To a mixture of 700 mg (1.90 mmol) of 1-butyl-6-ethyl-N-(2,6-diethylphenyl)-1,4-dihydro-2-methyl-4-oxo-3-pyridinecarboxamide, 14 ml of methylene chloride and 1.2 g (7.40 mmol) of sodium carbonate was added a solution of 303 mg (1.90 mmol) of bromine in 5 ml of methylene chloride under vigorous stirring. After the completion of addition the mixture was stirred for 6 hours. The insoluble product in methylene chloride was filtered off and the filtrate was concentrated in vacuo to give a crystalline residue. The residue was recrystallized from benzene and cyclohexane to afford 615 mg of the title compound having mp. 132.5°-133.5° C.

EXAMPLE 4 1,4-dihydro-2-methyl-4-oxo-N,5-diphenyl-1-phenylmethyl -3-pyridinecarboxamide

To a mixture of 2.66 g (10 mmol) of 3-benzylaminocrotonanilide, 0.87 g (11 mmol) of pyridine and 30 ml of methylene chloride was added a mixture of 1.45 ml (11 mmol) of phenylacetylchloride and 5 ml of methylene chloride under ice cooling. After the mixture was stirred for 2.5 hours under ice cooling, it was poured into ice water and extracted. The organic layer was dried and concentrated in an usual manner and the residue was crystallized form benzene and diethylether to afford 1.81 g of 2-phenylacetyl-3-phenylmethylamino-2-butenoylanilide. A mixture of 1.60 g (4.16 mmol) of 2-phenylacetyl-3-phenylmethylamino-2-butenoylanilide, 2.23 g of N,N-dimethylformamide dimethylacetal, 0.2 ml of triethylamine and 5 ml of benzene was refluxed for 80 minutes under nitrogen atmosphere. The reaction mixture was concentrated under vacuo to give an oily residue, which was purified by column chromatography and crystallization from ethylacetate to afford 0.70 g of the title compound.

The following Table 1 and Table 2 show physical properties of the compounds associated with this invention. Numbers in the column "Evaluation" in Table 2 were obtained as follows:

A carrier was prepared by mixing 50 parts (by weight) of talc, 25 parts of bentonite, 2 parts of Solpole-9047 (Toho Chemical Co., Ltd, Japan) and 3 parts of Solpole-5039 (Toho Chemical Co., Ltd, Japan). 50 parts of a test compound and 200 parts of the carrier were mixed to obtain 20% wettable powder, followed by dispersing the powder in distilled water to make a dispersion of the definite concentrations.

Seeds of Oryza sativa L., Echinochloa crus-galli L., and Raphanus sativus L. were germinated in a laboratory dish, to which the dispersion was added. After breeding for 7 days in a thermostatic box kept at 25° C. under illumination of fluorescent tubes, growth of plant was observed. In the column of "Evaluation" of Table 2, the designation 1 denotes no influence, 2 denotes 25% growth inhibition, 3 denotes 50% growth inhibition, 4 denotes 75% growth inhibition and 5 denotes 100% growth inhibition.

                                      TABLE 1                                      __________________________________________________________________________     Example                                    Melting                                                                              Molecular                     NO.   R       R.sub.2                                                                               R.sub.3                                                                             R.sub.4                                                                            R.sub.5                                                                            R.sub.6                                                                             R.sub.7                                                                            point (°C.)                                                                   formula Method                __________________________________________________________________________     1     phenylmethyl                                                                           C.sub.2 H.sub.5                                                                       H    H   H   H    CH.sub.3                                                                           155-157                                                                              C.sub.22 H.sub.22                                                              N.sub.2 O.sub.2                                                                        A                     2     4-methyl                                                                               "      "    "   "   "    "   153-154                                                                              C.sub.23 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                           phenylmethyl                                                             3     butyl   n-C.sub.3 H.sub.7                                                                     "    "   "   "    "   116-117                                                                              C.sub.20 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     4     phenylmethyl                                                                           "      "    "   "   "    "   150-152                                                                              C.sub.23 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                     5     2-phenylethyl                                                                          "      "    "   "   "    "   132-133                                                                              C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     6     phenylmethyl                                                                           n-C.sub.4 H.sub.9                                                                     "    "   "   "    "   132-134                                                                              C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     7     4-methyl                                                                               "      "    "   "   "    "         C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                           phenylmethyl                                                             8     phenylmethyl                                                                           iso-C.sub.4 H.sub.9                                                                   "    "   "   "    "   112.5-114                                                                            C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     9     "       n-C.sub.5 H.sub.11                                                                    "    "   "   "    "   114-115.5                                                                            C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     10    "       n-C.sub.7 H.sub.15                                                                    "    "   "   "    "   86-88 C.sub.27 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     11    "       n-C.sub.9 H.sub.19                                                                    "    "   "   "    "         C.sub.29 H.sub.36                                                              N.sub.2 O.sub.2                                                                        A                     12    "       phenylmethyl                                                                          "    "   "   "    "   190.5-193                                                                            C.sub.27 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                     13    4-methyl                                                                               phenylmethyl                                                                          H    H   H   H    CH.sub.3                                                                           188-189                                                                              C.sub.28 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                           phenylmethyl                                                             14    H       phenyl "    "   "   "    "   277-279                                                                              C.sub.19 H.sub.16                                                              N.sub.2 O.sub.2                                                                        B                     15    methyl  "      "    "   "   "    "   215-217                                                                              C.sub.20 H.sub.18                                                              N.sub.2 O.sub.2                                                                        B                     16    ethyl   "      "    "   "   "    "   207-209                                                                              C.sub.21 H.sub.20                                                              N.sub.2 O.sub.2                                                                        B                     17    propyl  "      "    "   "   "    "   180-183                                                                              C.sub.22 H.sub.22                                                              N.sub.2 O.sub.2                                                                        B                     18    butyl   "      "    "   "   "    "   189.5-193                                                                            C.sub.23 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                     19    pentyl  "      "    "   "   "    "   170.5-173                                                                            C.sub.24 H.sub.26                                                              N.sub.2 O.sub.                                                                         B                     20    hexyl   "      "    "   "   "    "   137-138.5                                                                            C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     21    octyl   "      "    "   "   "    "         C.sub.27 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     22    3-      "      "    "   "   "    "   203-204.5                                                                            C.sub.23 H.sub.24                                                              N.sub.2 O.sub.3                                                                        A                           methoxypropyl                                                            23    2-      "      "    "   "   "    "   191-192                                                                              C.sub.22 H.sub.22                                                              N.sub.2 O.sub.3                                                                        A                           methoxyethyl                                                             24    phenyl  "      "    "   "   "    "   more than                                                                            C.sub.25 H.sub.20                                                              N.sub.2 O.sub.2                                                                        A                                                                300° C.                      25    phenylmethyl                                                                           phenyl H    H   H   H    CH.sub.3                                                                           185.5-187.5                                                                          C.sub.26 H.sub.22                                                              N.sub.2 O.sub.2                                                                        A                     26    4-methyl                                                                               "      "    "   "   "    "   191.5-193                                                                            C.sub.27 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                           phenylmethyl                                                             27    4-chloro                                                                               "      "    "   "   "    "   198-200                                                                              C.sub.26 H.sub.21                                                              ClN.sub.2 O.sub.2                                                                      A                           phenylmethyl                                                             28    2-phenylethyl                                                                          "      "    "   "   "    "   168-171                                                                              C.sub.27 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                     29    2-furylmethyl                                                                          "      "    "   "   "    "         C.sub.24 H.sub.20                                                              N.sub.2 O.sub.                                                                         A                     30    2-      "      "    "   "   "    "   209-211                                                                              C.sub.25 H.sub.21                                                              N.sub.3 O.sub.2                                                                        A                           pyridylmethyl                                                            31    phenylmethyl                                                                           3-chloro                                                                              "    "   "   "    "   227-229                                                                              C.sub.26 H.sub.21                                                              ClN.sub.2 O.sub.2                                                                      A                                   phenyl                                                           32    "       4-chloro                                                                              "    "   "   "    "   222.5-228                                                                            C.sub.26 H.sub.21                                                              ClN.sub.2 O.sub.2                                                                      A                                   phenyl                                                           33    "       4-methyl                                                                              "    "   "   "    "   172-175                                                                              C.sub.27 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                                   phenyl                                                           34    "       2-furyl                                                                               "    "   "   "    "         C.sub.24 H.sub.20                                                              N.sub.2 O.sub.3                                                                        A                     35    "       n-C.sub.3 H.sub.7                                                                     2-CH.sub.3                                                                          "   "   "    "   139-140.5                                                                            C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     36    4-chloro                                                                               "      "    "   "   "    "   124-125                                                                              C.sub.24 H.sub.25                                                              ClN.sub.2 O.sub.2                                                                      A                           phenylmethyl                                                             37    2-phenylethyl                                                                          n-C.sub.3 H.sub.7                                                                     2-CH.sub.3                                                                          H   H   H    CH.sub.3                                                                           132.5-134.5                                                                          C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     38    butyl   phenyl "    "   "   "    "   166.5-168.0                                                                          C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     39    phenylmethyl                                                                           "      "    "   "   "    "   231-233                                                                              C.sub.27 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                     40    4-chloro                                                                               "      "    "   "   "    "   106-109                                                                              C.sub.27 H.sub.23                                                              ClN.sub.2 O.sub.2                                                                      A                           phenylmethyl                                                             41    butyl   "      2-Cl "   "   "    "   174-175                                                                              C.sub.23 H.sub.23                                                              ClN.sub.2 O.sub.2                                                                      A                     42    "       "      2-CH.sub.3                                                                          3-CH.sub.3                                                                         "   "    "   221-224                                                                              C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     43    phenylmethyl                                                                           "      "    "   "   "    "   214-216                                                                              C.sub.28 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     44    2-phenylethyl                                                                          "      "    "   "   "    "   215-217.5                                                                            C.sub.29 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     45    butyl   "      2-CH.sub.3                                                                          6-CH.sub.3                                                                         "   "    "   166-168.5                                                                            C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     46    phenylmethyl                                                                           "      "    "   "   "    "         C.sub.28 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                     47    butyl   H      2-C.sub. 2 H.sub.5                                                                  6-C.sub.2 H.sub.5                                                                  "   "    "   151-152.5                                                                            C.sub.21 H.sub.28                                                              N.sub.2 O.sub.2                                                                         C'                   48    "       C.sub.2 H.sub.5                                                                       "    "   "   "    "         C.sub.23 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     49    phenylmethyl                                                                           C.sub.2 H.sub.5                                                                       2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  H   H    CH.sub.3  C.sub.26 H.sub.30                                                              N.sub.2 O.sub.2                                                                        A                     50    2-phenylethyl                                                                          "      "    "   "   "    "         C.sub.27 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     51    propyl  n-C.sub.3 H.sub.7                                                                     "    "   "   "    "         C.sub.23 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     52    butyl   "      "    "   "   "    "         C.sub.24 H.sub.34                                                              N.sub.2 O.sub.2                                                                        A                     53    phenylmethyl                                                                           "      "    "   "   "    "   152-154                                                                              C.sub.27 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     54    butyl   n-C.sub.4 H.sub.9                                                                     "    "   "   "    "         C.sub.25 H.sub.36                                                              N.sub.2 O.sub.2                                                                        A                     55    "       iso-C.sub.4 H.sub.9                                                                   "    "   "   "    "         C.sub.25 H.sub.36                                                              N.sub.2 O.sub.2                                                                        A                     56    "       phenylmethyl                                                                          "    "   "   "    "         C.sub.28 H.sub.34                                                              N.sub.2 O.sub.2                                                                        A                     57    "       phenyl "    "   "   "    "   152-153                                                                              C.sub.27 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     58    phenyl  "      "    "   "   "    "   more than                                                                            C.sub.29 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                                                                300° C.                      59    phenylmethyl                                                                           "      "    "   "   "    "   100-103                                                                              C.sub.30 H.sub.30                                                              N.sub.2 O.sub.2                                                                        A                     60    2-phenylmethyl                                                                         phenyl "    "   "   "    "   196-197.5                                                                            C.sub.31 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                     61    2-methylphenyl                                                                         phenyl 2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  H   H    CH.sub.3                                                                           162.5-163.5                                                                          C.sub.30 H.sub.30                                                              N.sub.2 O.sub.2                                                                        A                     62    phenyl  4-     "    "   "   "    "   297-299                                                                              C.sub.30 H.sub.30                                                              N.sub.2 O.sub.2                                                                        A                                   methylphenyl                                                     63    butyl   C.sub.2 H.sub.5                                                                       "    "   "   Br   "         C.sub.23 H.sub.31                                                              BrN.sub.2 O.sub.2                                                                      D                     64    phenylmethyl                                                                           CH.sub.3                                                                              H    H   "   H    C.sub.2 H.sub.5                                                                    135-137                                                                              C.sub.22 H.sub.22                                                              N.sub.2 O.sub.2                                                                        B                     65    "       "      "    "   "   "    n-C.sub.3 H.sub.7                                                                  112-113                                                                              C.sub.23 H.sub.24                                                              N.sub.2 O.sub.2                                                                        B                     66    butyl   "      "    "   "   "    phenyl                                                                             181-183                                                                              C.sub.23 H.sub.24                                                              N.sub.2 O.sub.2                                                                        B                     67    phenylmethyl                                                                           "      "    "   "   "    "   104-106                                                                              C.sub.26 H.sub.22                                                              N.sub.2 O.sub.2                                                                        B                     68    "       "      "    "   "   "    CF.sub.3                                                                           78-80 C.sub.21 H.sub.17                                                              F.sub.3 N.sub.2 O.sub.2                                                                B                     69    butyl   "      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  "   "    C.sub.2 H.sub.5                                                                    112.5-114.5                                                                          C.sub.23 H.sub.32                                                              N.sub.2 O.sub.2                                                                        B                     70    phenylmethyl                                                                           "      "    "   "   "    "   133.5-135                                                                            C.sub.26 H.sub.30                                                              N.sub.2 O.sub.2                                                                        B                     71    2-phenylethyl                                                                          "      "    "   "   "    "   109-111                                                                              C.sub.27 H.sub.32                                                              N.sub.2 O.sub.2                                                                        B                     72    butyl   "      "    "   "   Br   "   132.5-133.5                                                                          C.sub.23 H.sub.31                                                              BrN.sub.2 O.sub.2                                                                      D                     73    2-      CH.sub.3                                                                              2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  H   Br   C.sub.2 H.sub.5                                                                    126-129.5                                                                            C.sub.27 H.sub.31                                                              BrN.sub.2 O.sub.2                                                                      D                           phenylethyl                                                              74    butyl   "      "    "   "   H    n-C.sub.3 H.sub.7                                                                        C.sub.24 H.sub.34                                                              N.sub.2 O.sub.2                                                                        B                     75    2-phenylethyl                                                                          "      "    "   "   "    "         C.sub.28 H.sub.34                                                              N.sub.2 O.sub.                                                                         B                     76    "       "      "    "   "   "    CF.sub.3                                                                           179-180                                                                              C.sub.26 H.sub.27                                                              F.sub.3 N.sub.2 O.sub.2                                                                B                     77    butyl   "      "    "   "   "    n-C.sub.4 H.sub.9                                                                        C.sub.25 H.sub.36                                                              N.sub.2 O.sub.2                                                                        B                     78    2-phenylethyl                                                                          "      "    "   "   "    "         C.sub.29 H.sub.36                                                              N.sub.2 O.sub.2                                                                        B                     79    butyl   "      "    "   phenyl                                                                             "    H   180-182                                                                              C.sub.27 H.sub.32                                                              N.sub.2 O.sub.2                                                                        F                     80    2-phenylethyl                                                                          "      "    "   H   --(CH.sub.2)4--                                                                         188-190                                                                              C.sub.29 H.sub.34                                                              N.sub.2 O.sub.2                                                                        B                     81    phenylmethyl                                                                           "      H    H   "   phenyl                                                                              H   166-168                                                                              C.sub.26 H.sub.22                                                              N.sub.2 O.sub.2                                                                        F                     82    cyclohexyl-                                                                            C.sub.2 H.sub.5                                                                       "    "   "   H    CH.sub.3  C.sub.22 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                           methyl                                                                   83    4-methyl-                                                                              n-C.sub. 3 H.sub.7                                                                    "    "   "   "    "   181-183                                                                              C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        A                           phenylmethyl                                                             84    cyclohexyl-                                                                            "      "    "   "   "    "         C.sub.23 H.sub.30                                                              N.sub.2 O.sub.2                                                                        A                           methyl                                                                   85    cyclohexyl-                                                                            n-C.sub.4 H.sub.9                                                                     H    H   H   H    CH.sub.3  C.sub.24 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                           methyl                                                                   86    4-methyl-                                                                              iso-C.sub.4 H.sub.9                                                                   "    "   "   "    "         C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                           phenylmethyl                                                             87    cyclohexyl-                                                                            "      "    "   "   "    "         C.sub.24 H.sub.32                                                              N.sub.2 O.sub.2                                                                        A                           methyl                                                                   88    4-methyl-                                                                              n-C.sub.5 H.sub.11                                                                    "    "   "   "    "   151-152.5                                                                            C.sub.26 H.sub.30                                                              N.sub.2 O.sub.2                                                                        A                           phenylmethyl                                                             89    phenylmethyl                                                                           C.sub.2 H.sub.5                                                                       2-CH.sub.3                                                                          "   "   "    "         C.sub.23 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                     90    4-chloro-                                                                              "      "    "   "   "    "         C.sub.23 H.sub.23                                                              ClN.sub.2 O.sub.2                                                                      A                           phenylmethyl                                                             91    phenylmethyl                                                                           nC.sub.4 H.sub.9                                                                      "    "   "   "    "   161-163.5                                                                            C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     92    4-chloro-                                                                              "      "    "   "   "    "         C.sub.25 H.sub.27                                                              ClN.sub.2 O.sub.2                                                                      A                           phenylmethyl                                                             93    phenylmethyl                                                                           nC.sub.5 H.sub.11                                                                     "    "   "   "    "   111.5-113                                                                            C.sub.26 H.sub.30                                                              N.sub.2 O.sub.2                                                                        A                     94    4-chloro-                                                                              "      "    "   "   "    "   155-156.5                                                                            C.sub.26 H.sub.29                                                              ClN.sub.2 O.sub.2                                                                      A                           phenylmethyl                                                             95    phenylmethyl                                                                           C.sub.2 H.sub.5                                                                       2-Cl "   "   "    "   174.5-177                                                                            C.sub.22 H.sub.21                                                              ClN.sub.2 O.sub.2                                                                      A                     96    phenylmethyl                                                                           nC.sub.3 H.sub.7                                                                      "    "   "   "    "   171-171.5                                                                            C.sub.22 H.sub.23                                                              ClN.sub.2 O.sub.2                                                                      A                     97    phenylmethyl                                                                           nC.sub.4 H.sub.9                                                                      2-Cl H   H   H    CH.sub.3                                                                           121-123                                                                              C.sub.24 H.sub.25                                                              ClN.sub.2 O.sub.2                                                                      A                     98    phenylmethyl                                                                           nC.sub.3 H.sub.7                                                                      2-CH.sub.3                                                                          3-CH.sub.3                                                                         "   "    "   126-128                                                                              C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        A                     99    phenylmethyl                                                                           methoxy-                                                                              H    H   "   "    "         C.sub.22 H.sub.22                                                              N.sub.2 O.sub.3                                                                        A                                   methyl                                                           100   phenylmethyl                                                                           2-methyl-                                                                             "    "   "   "    "   173-174                                                                              C.sub.27 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                                   phenyl                                                           101   phenylmethyl                                                                           3-methyl-                                                                             "    "   "   "    "   202.5-204.5                                                                          C.sub.27 H.sub.24                                                              N.sub.2 O.sub.2                                                                        A                                   phenyl                                                           102   phenylmethyl                                                                           2-chloro-                                                                             "    "   "   "    "   194-196                                                                              C.sub.26 H.sub.21                                                              ClN.sub.2 O.sub.2                                                                      A                                   phenyl                                                           103   phenylmethyl                                                                           2-furyl                                                                               "    "   "   "    "         C.sub.24 H.sub.20                                                              N.sub.2 O.sub.3                                                                        A                     104   methyl  nC.sub.4 H.sub.9                                                                      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  "   "    "   95.5-96                                                                              C.sub.22 H.sub.30                                                              N.sub.2 O.sub.2                                                                        B                     105   methyl  "      "    "   "   Br   "   180-180.5                                                                            C.sub.22 H.sub.29                                                              BrN.sub.2 O.sub.                                                                       D                     106   methyl  "      "    "   "   CH.sub.3                                                                            CH.sub.3                                                                           114.5-115.5                                                                          C.sub.23 H.sub.32                                                              N.sub.2 O.sub.2                                                                        B                     107   methyl  "      "    "   4-Br                                                                               H    "   170.5-171.0                                                                          C.sub.22 H.sub.29                                                              BrN.sub.2 O.sub.2                                                                      B                     108   methyl  "      "    "   "   Br   "   179.5-180                                                                            C.sub.22 H.sub.28                                                              Br.sub.2 N.sub.2                                                                       D.sub.2               109   methyl  nC.sub.4 H.sub.9                                                                      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  4-Br                                                                               CH.sub.3                                                                            CH.sub.3                                                                           139.0-140.0                                                                          C.sub.23 H.sub.31                                                              BrN.sub.2 O.sub.2                                                                      B                     110   methyl  nC.sub.3 H.sub.7                                                                      "    "   H   "    "   148-150.5                                                                            C.sub.26 H.sub.30                                                              N.sub.2 O.sub.2                                                                        B                     111   methyl  "      "    "   4-Br                                                                               "    "   156.0-156.5                                                                          C.sub.26 H.sub.29                                                              BrN.sub.2 O.sub.2                                                                      B                     112   methyl  nC.sub.5 H.sub.11                                                                     "    "   H   H    "   98-98.5                                                                              C.sub.24 H.sub.34                                                              N.sub.2 O.sub.2                                                                        B                     113   3-chlorophenyl                                                                         nC.sub.4 H.sub.9                                                                      H    H   "   "    "   210-211                                                                              C.sub.23 H.sub. 23                                                             ClN.sub.2 O.sub.2                                                                      B                     114   3-bromophenyl                                                                          "      "    "   "   "    "   204-205                                                                              C.sub.23 H.sub.23                                                              BrN.sub.2 O.sub.2                                                                      B                     115   3,5-bistri-                                                                            "      "    "   "   "    "   248-249                                                                              C.sub.25 H.sub.22                                                              F.sub.6 N.sub.2 O.sub.2                                                                B                           fluoromethyl-                                                                  phenyl                                                                   116   3-trifluoro                                                                            "      "    "   "   "    "   175-176                                                                              C.sub.24 H.sub.23                                                              F.sub.3 N.sub.2 O.sub.2                                                                B                           methylphenyl                                                             117   3-methylphenyl                                                                         "      "    "   "   "    "   110.5-111                                                                            C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        B                     118   3-iodophenyl                                                                           "      "    "   "   "    "   211.5-216.5                                                                          C.sub.23 H.sub.23                                                              IN.sub.2 O.sub.2                                                                       B                     119   3-fluorophenyl                                                                         "      "    "   "   "    "   185.5-187                                                                            C.sub.23 H.sub.23                                                              FN.sub.2 O.sub.2                                                                       B                     120   3-ethylphenyl                                                                          "      "    "   "   "    "   142-142.5                                                                            C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        B                     121   3,5-dichloro-                                                                          nC.sub.4 H.sub.9                                                                      H    H   H   H    CH.sub.3                                                                           218-218.5                                                                            C.sub.23 H.sub.22                                                              Cl.sub.2 N.sub.2                                                                       B.sub.2                     phenyl                                                                   122   3-methoxyphenyl                                                                        n-C.sub.4 H.sub.9                                                                     "    "   "   "    "   140-142                                                                              C.sub.24 H.sub.26                                                              N.sub.2 O.sub.3                                                                        B                     123   2,3-dichloro-                                                                          "      "    "   "   "    "   178-180                                                                              C.sub.23 H.sub.22                                                              ClN.sub.2 O.sub.2                                                                      B                           phenyl                                                                   124   3,4-dichloro-                                                                          "      "    "   "   "    "   199.5-200.0                                                                          C.sub.23 H.sub.22                                                              Cl.sub.2 N.sub.2                                                                       B.sub.2                     phenyl                                                                   125   3-chlorophenyl                                                                         "      2-CH.sub.3                                                                          3-CH.sub.3                                                                         "   "    "   123-124                                                                              C.sub.25 H.sub.27                                                              ClN.sub.2 O.sub.2                                                                      B                     126   3-chlorophenyl                                                                         "      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  "   "    "   178-178.5                                                                            C.sub.27 H.sub.31                                                              ClN.sub.2 O.sub.2                                                                      B                     127   3-chlorophenyl                                                                         phenyl "    "   "   "    "   242-243                                                                              C.sub.29 H.sub.27                                                              ClN.sub.2 O.sub.2                                                                      B                     128   H       nC.sub.4 H.sub.9                                                                      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  H   H    CH.sub.3                                                                           oil   C.sub.21 H.sub.28                                                              N.sub.2 O.sub.2                                                                        B                     129   H       3-bromo-                                                                              H    H   "   "    "   286.5-289                                                                            C.sub.19 H.sub.15                                                              BrN.sub.2 O.sub.2                                                                      B                                   phenyl                                                           130   methyl  nC.sub.3 H.sub.7                                                                      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  "   "    "   99.5-100.5                                                                           C.sub.21 H.sub.28                                                              N.sub.2 O.sub.2                                                                        B                     131   methyl  "      "    "   4-Br                                                                               "    "   159.0-160.0                                                                          C.sub.21 H.sub.27                                                              BrN.sub.2 O.sub.2                                                                      B                     132   methyl  "      "    "   4-I "    "         C.sub.21 H.sub.27                                                              IN.sub.2 O.sub.2                                                                       B                     133   methyl  nC.sub.3 H.sub.7                                                                      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  4-OCH.sub.3                                                                        H    CH.sub.3  C.sub.22 H.sub.30                                                              N.sub.2 O.sub.3                                                                        B                     134   methyl  "      "    "   4-C.sub.2 H.sub.5                                                                  "    "         C.sub.23 H.sub.32                                                              N.sub.2 O.sub.2                                                                        B                     135   methyl  3-chloro-                                                                             H    H   H   "    "   191.0-192.5                                                                          C.sub.20 H.sub.17                                                              ClN.sub.2 O.sub.2                                                                      B                                   phenyl                                                           136   ethyl   nC.sub.4 H.sub.9                                                                      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  4-Br                                                                               "    "   143.5-145                                                                            C.sub.23 H.sub.31                                                              BrN.sub.2 O.sub.2                                                                      B                     137   H       "      "    "   H   Br   CH.sub.3                                                                           163-166                                                                              C.sub.21 H.sub.27                                                              BrN.sub.2 O.sub.2                                                                      D                     138   methyl  nC.sub.3 H.sub.7                                                                      "    "   "   "    "   183-184.5                                                                            C.sub.21 H.sub.27                                                              BrN.sub.2 O.sub.2                                                                      D                     139   methyl  "      "    "   4-Br                                                                               "    "   204-205                                                                              C.sub.21 H.sub.26                                                              Br.sub.2 N.sub.2                                                                       D.sub.2               140   methyl  "      "    "   4-C.sub.2 H.sub.5                                                                  "    "   169-173.5                                                                            C.sub.23 H.sub.31                                                              BrN.sub.2 O.sub.2                                                                      D                     141   ethyl   nC.sub.4 H.sub.9                                                                      "    "   4-Br                                                                               "    "   210-210.5                                                                            C.sub.23 H.sub.30                                                              Br.sub.2 N.sub.2                                                                       D.sub.2               142   methyl  nC.sub.3 H.sub.7                                                                      "    "   4-C.sub.2 H.sub.5                                                                  CH.sub.3                                                                            "         C.sub.24 H.sub.34                                                              N.sub.2 O.sub.2                                                                        B                     143   methyl  "      "    "   4-I "    "         C.sub.22 H.sub.29                                                              IN.sub.2 O.sub.2                                                                       B                     144   methyl  nC.sub.4 H.sub.9                                                                      "    "   4-Br                                                                               C.sub.2 H.sub.5                                                                     "   oil   C.sub.24 H.sub.33                                                              BrN.sub.2 O.sub.2                                                                      B                     145   methyl  nC.sub.3 H.sub.7                                                                      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  H   H    C.sub.2 H.sub.5                                                                          C.sub.22 H.sub.30                                                              N.sub.2 O.sub.2                                                                        B                     146   methyl  nC.sub.4 H.sub.9                                                                      "    "   4-Br                                                                               CH.sub.3                                                                            "         C.sub.24 H.sub.33                                                              BrN.sub.2 O.sub.2                                                                      B                     147   phenyl  "      H    H   H   H    CH.sub.3                                                                           213.0-214.0                                                                          C.sub.23 H.sub.24                                                              N.sub.2 O.sub.2                                                                        B                     148   2-methylphenyl                                                                         "      "    "   "   "    "   183.0-185.0                                                                          C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        B                     149   2-chlorophenyl                                                                         "      "    "   "   "    "   153.0-154.0                                                                          C.sub.23 H.sub.23                                                              ClN.sub.2 O.sub.2                                                                      B                     150   methyl  phenyl 2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  "   CH.sub.3                                                                            "         C.sub.25 H.sub.28                                                              N.sub.2 O.sub.2                                                                        B                     151   3-cyanophenyl                                                                          nC.sub.4 H.sub.9                                                                      H    H   "   H    "   207.5-209.5                                                                          C.sub.24 H.sub.23                                                              N.sub.3 O.sub.2                                                                        B                     152   3-nitrophenyl                                                                          "      "    "   "   "    "   184.5-186                                                                            C.sub.23 H.sub.23                                                              N.sub.3 O.sub.4                                                                        B                     153   4-chlorophenyl                                                                         "      "    "   "   "    "   192.0-192.5                                                                          C.sub.23 H.sub.23                                                              ClN.sub.2 O.sub.2                                                                      B                     154   4-methylphenyl                                                                         "      "    "   "   "    "   163.5-165.0                                                                          C.sub.24 H.sub.26                                                              N.sub.2 O.sub.2                                                                        B                     155   3-chloro-2-                                                                            "      "    "   "   "    "   163.0-164.0                                                                          C.sub.24 H.sub.25                                                              ClN.sub.2 O.sub.2                                                                      B                           methylphenyl                                                             156   3-chloro-4-                                                                            "      "    "   "   "    "         C.sub.24 H.sub.25                                                              ClN.sub.2 O.sub.2                                                                      B                           methylphenyl                                                             157   5-chloro-2-                                                                            nC.sub.4 H.sub.9                                                                      H    H   H   H    CH.sub.3  C.sub.24 H.sub.25                                                              ClN.sub.2 O.sub.2                                                                      B                           methylphenyl                                                             158   3-pyridyl                                                                              "      "    "   "   "    "         C.sub.22 H.sub.23                                                              N.sub.3 O.sub.2                                                                        B                     159   3-bromophenyl                                                                          "      2-CH.sub.3                                                                          3-CH.sub.3                                                                         "   "    "   157.5-158.0                                                                          C.sub.25 H.sub.27                                                              BrN.sub.                                                                               B O.sub.2             160   3-methylphenyl                                                                         "      "    "   "   "    "   165.0-166.5                                                                          C.sub.26 H.sub.30                                                              N.sub.2 O.sub.2                                                                        B                     161   3-trifluoro-                                                                           "      "    "   "   "    "   157.5-158.0                                                                          C.sub.26 H.sub.27                                                              F.sub.3 N.sub.2 O.sub.2                                                                B                           methylphenyl                                                             162   3-bromophenyl                                                                          "      2-C.sub.2 H.sub.5                                                                   6-C.sub.2 H.sub.5                                                                  "   "    "   136.5-137.5                                                                          C.sub.27 H.sub.31                                                              BrN.sub.2 O.sub.2                                                                      B                     163   3-trifluoro-                                                                           "      "    "   "   "    "         C.sub.28 H.sub.31                                                              F.sub.3 N.sub.2 O.sub.2                                                                B                           methylphenyl                                                             164   methyl  n-C.sub.3 H.sub.7                                                                     "    "   "   Br   C.sub.2 H.sub.5                                                                          C.sub.22 H.sub.29                                                              BrN.sub.2 O.sub.2                                                                      D                     165   methyl  "      "    "   4-OCH.sub.3                                                                        "    CH.sub.3  C.sub.22 H.sub.29                                                              BrN.sub.2 O.sub.3                                                                      D                     166   methyl  "      "    "   I   "    "         C.sub.21 H.sub.26                                                              BrIN.sub.2 O.sub.2                                                                     D                     __________________________________________________________________________

                                      TABLE 2                                      __________________________________________________________________________                                             Evaluation                             Example                                                                             IR           NMR                   Conc.                                                                              Plants                             No.  ν value (cm.sup.-1)                                                                 Method                                                                              Chemical shift δ value                                                                  Solvent                                                                               (ppm)                                                                              X Y Z                              __________________________________________________________________________     1    1617,   KBr  1.40 (3H,t), 2.26 (3H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1663         3.40 (2H,q), 5.22 (2H,s),                                                                            100 4 4 2                                                6.43 (1H,s),                                                                   6.70-7.75(10H,m),                                                              12.76(1H,br)                                                 2    1600,   KBr  1.37 (3H,t), 2.26 (3H,s),                                                                     "       20 4 4 1                                   1638,        2.32 (3H,s), 3.25 (2H,q),                                                                            100 4 4 1                                   1664         5.18 (2H,s), 6.43 (1H,s),                                                      6.60-7.75 (9H,m),                                                              12.83 (1H,br)                                                3    1630,   KBr  1.04 (6H,t), 0.7-2.0 (6h,m),                                                                  "       20 3 4 3                                   1675         2.31 (3H,s), 3.27 (2H,t),                                                                            100 3 4 3                                                3.87 (2H,t), 6.31 (1H,s),                                                      6.90-7.60 (5H,m),                                                              12.60 (1H,br)                                                4    1627,   KBr  0.98 (3H,t), 1.80 (2H,six),                                                                   "        20                                                                               4 4 1                                   1667         2.24 (3H,s), 3.18 (2H,t),                                                                            100 4 4 1                                                5.16 (2H,s), 6.40 (1H,s),                                                      6.70-7.70 (10H,m),                                                             12.75 (1H,br)                                                5    1625,   KBr  1.07 (3H,t), 1.63 (2H,six),                                                                   "       20 3 4 1                                   1673         2.31 (3H,s), 2.91 (2H,t),                                                                            100 3 4 1                                                3.36 (2H,t), 4.10 (2H,t),                                                      6.32 (1H,s), 6.90-7.70 (10H,m),                                                12.69 (1H,br)                                                6    1630,   KBr  0.89 (3H,t), 1.00-2.00 (4H,m),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1675         2.25 (3H,s), 3.22 (2H,t),                                                                            100 4 4 2                                                5.19 (2H,s), 6.41 (1H,s),                                                      6.70-7.70 (10H,m), 12.70 (1H,br)                             7    1640,   KBr  0.92 (3H,t), 1.10-2.20 (4H,m),                                                                "       20 4 4 1                                   1665         2.24 (3H,s), 2.30 (3H,s),                                                                            100 4 4 1                                                3.25 (2H,t), 5.15 (2H,s),                                                      6.41 (1H,s), 6.70-7.75 (9H,m),                                                 12.74 (1H,br)                                                8    1620,   KBr  0.95 (6H,d), 2.90 (1H,m),                                                                     "       20 4 4 1                                   1660         2.23 (3H,s), 3.46 (2H,d),                                                                            100 4 4 1                                                5.20 (2H,s), 6.41 (1H,s),                                                      6.70-7.70 (10H,m),                                                             12.42 (1H,br)                                                9    1627,   KBr  0.87 (3H,t,), 1.00-2.10 (6H,m),                                                               "       20 4 4 1                                   1670         2.22 (3H,s), 3.23 (2H,t),                                                                            100 4 4 1                                                5.16 (2H,s), 6.40 (1H,s),                                                      6.70-7.70 (10H,m),                                                             12.63 (1H,br)                                                10   1637,   KBr  0.83 (3H,t), 1.00-2.00 (10H,m),                                                               "       20 3 4 1                                   1663         2.22 (3H,s), 3.20 (2H,t),                                                                            100 4 4 1                                                5.14 (2H,s), 6.36 (1H,s),                                                      6.70-7.75 (10H,m),                                                             12.70 (1H,br)                                                11   1600,   Neat 0.86 (3H,t), 0.90-2.00 (14H,m),                                                               CDCl.sub.3                                                                             20 3 4 1                                   1630,        2.24 (3H,s), 3.20 (2H,t),                                                                            100 3 4 1                                   1670         5.18 (2H,s), 6.40 (1H,s),                                                      6.70-7.70 (10H,m), 12.65 (1H,br)                             12   1623,   KBr  2.23 (3H,s), 4.70 (2H,s),                                                                     "       20 1 4 1                                   1660         5.00 (2H,s), 6.47 (1H,s),                                                                            100 1 4 1                                                6.60-7.65 (15H,m),                                                             12.83 (1H,br)                                                13   1627,   KBr  2.20 (3H,s), 2.31 (3H,s),                                                                     "       20 2 4 1                                   1657         4.73 (2H,s), 5.00 (2H,s),                                                                            100 2 4 1                                                6.50 (1H,s), 6.65-7.70 (15H,m),                                                12.83 (1H,br)                                                14   1610,   KBr                         20 1 3 1                                   1640,                              100 2 4 1                                   1660                                                                      15   1625,   KBr  2.36 (3H,s), 3.14 (3H,s),                                                                     CDCl.sub.3                                                                             20 2 3 3                                   1663         6.51 (1H,s),          100 2 4 5                                                6.85-7.60 (10H,m),                                                             12.53 (1H,br)                                                16   1617,   KBr  1.06 (3H,t), 2.42 (3H,s),                                                                     CDCl.sub.3                                                                             20 1 4 1                                   1663         3.68 (2H,q), 6.51 (1H,s),                                                                            100 4 4 1                                                6.90-7.60 (10H,m),                                                             12.45 (1H,br)                                                17   1617,   KBr  0.59 (3H,t), 1.45 (2H,six),                                                                   "       20 4 4 1                                   1677         2.40 (3H,s), 3.48 (2H,t),                                                                            100 4 4 1                                                6.48 (1H,s), 6.80-7.65 (10H,m),                                                12.50 (1H,br)                                                18   1600,   KBr  0.66 (3H,t), 0.50-1.80 (4H,m),                                                                "       20 3 4 1                                   1617,        2.40 (3H,s), 3.58 (2H,t),                                                                            100 3 4 2                                   1680         6.51 (1H,s), 6.60- 7.65 (10H,m),                                               12.49 (1H,br)                                                19   1617,   KBr  0.71 (3H,t), 0.50-1.70 (6H,m),                                                                "       20 4 4 1                                   1675         2.38 (3H,s), 3.50 (2H,t),                                                                            100 4 4 3                                                6.32 (1H,s), 6.80-7.50 (10H,m),                                                12.53 (1H,br)                                                20   1617,   KBr  0.77 (3H,t), 0.50-1.80 (8H,m),                                                                "       20 4 4 1                                   1675         2.41 (3H,s), 3.57 (2H,t),                                                                            100 4 4 1                                                6.51 (1H,s), 6.85-7.60 (10H,m),                                                12.57 (1H,br)                                                21   1600,   KBr  0.58 (3H,t), 0.40-1.60 (12H,m),                                                               CDCl.sub.3                                                                             20 4 4 1                                   1620,        2.38 (3H,s), 3.66 (2H,t),                                                                            100 4 4 1                                   1680         6.43 (1H,s), 6.80-7.50 (10H,m),                                                12.07 (1H,br)                                                22   1617,   KBr  1.67 (2H,m), 2.40 (3H,s),                                                                     "       20 3 4 1                                   1677         3.00 (2H,t), 3.12 (3H,s),                                                                            100 3 5 1                                                3.70 (2H,t), 6.48 (1H,s),                                                      6.80-7.60 (10H,m), 12.46 (1H,br)                             23   1623,   KBr  2.44 (3H,s), 3.12 (3H,s),                                                                     "       20 4 4 1                                   1670         3.22 (2H,t), 3.85 (2H,t),                                                                            100 4 4 1                                                6.48 (1H,s), 6.80-7.60 (10H,m),                                                12.35 (1H,br)                                                24   1623,   KBr                        20  1 4 1                                   1675                               100 1 4 1                              25   1620,   KBr  2.27 (3H,s), 4.89 (2H,s)                                                                      CDCl.sub.3                                                                             20 4 4 1                                   1675         6.59 (1H,s), 6.55-7.60 (15H,m),                                                                      100 4 4 1                                                12.46 (1H,br)                                                26   1620,   KBr  2.25 (3H,s), 2.28 (3H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1673         4.79 (2H,s), 6.55 (1H,s),                                                                            100 4 4 1                                                6.50-7.60 (14H,m),                                                             12.48 (1H,br)                                                27   1625,   KBr  2.25 (3H,s), 4.80 (2H,s),                                                                     "       20 4 4 1                                   1665         6.58 (1H,s),          100 4 4 1                                                6.55-7.60 (14H,m),                                                             12.38 (1H,br)                                                28   1613,   KBr  2.42 (3H,s), 2.68 (2H,t),                                                                     "       20 1 4 1                                   1673         3.80 (2H,t), 6.52 (1H,t),                                                                            100 3 4 1                                                6.50-7.60 (15H,m),                                                             12.43 (1H,br)                                                29   1623,   KBr  2.43 (3H,s), 4.78 (2H,s),                                                                     "       20 4 4 1                                   1673         5.75 (1H,m), 6.20 (1H,dd),                                                                           100 4 4 1                                                6.50 (1H,s), 6.80-7.55 (11H,m),                                                12.35 (1H,br)                                                30   1617,   KBr  2.30 (3H,s), 4.91 (2H,s),                                                                     "       20 4 4 1                                   1667         6.58 (1H,s),          100 4 4 1                                                6.50-8.45 (14H,m),                                                             12.53 (1H,br)                                                31   1615,   KBr  2.30 (3H,s), 4.82 (2H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1665         6.59 (1H,s),          100 4 4 1                                                6.60-7.60 (14H,m),                                                             12.60 (1H,br)                                                32   1623,   KBr  2.26 (3H,s), 4.82 (2H,s),                                                                     "                                                  1670         6.57 (1H,s),                                                                   6.55-7.60 (14H,m),                                                             12.55 (1H,br)                                                33   1623,   KBr  2.22 (3H,s), 2.30 (3H,s)                                                                      "       20 3 4 1                                   1673         4.82 (2H,s), 6.52 (1H,s),                                                                            100 3 4 1                                                6.55-7.60 (14H,m),                                                             12.39 (1H,br)                                                34   1625,   Neat 2.23 (3H,s), 4.86 (2H,s)                                                                      "       20 4 4 1                                   1675         6.18 (1H,m), 6.35 (1H,dd),                                                                           100 4 4 3                                                6.57 (1H,s), 6.70-7.70 (11H,m),                                                12.30 (1H,br)                                                35   1623,   KBr  1.00 (3H,t), 1.75 (2H,six),                                                                   "       20 4 4 1                                   1660         2.24 (3H,s), 2.40 (3H,s),                                                                            100 4 4 1                                                3.20 (2H,t), 5.17 (2H,s),                                                      6.39 (1H,s), 5.17 (2H,s),                                                      12.43 (1H,br)                                                36   1630,   KBr  1.00 (3H,t), 1.75 (2H,six)                                                                    CDCl.sub.3                                                                             20 4 4 1                                   1675         2.21 (3H,s), 2.39 (3H,s),                                                                            100 4 4 2                                                3.20 (2H,t), 5.11 (2H,s),                                                      6.38 (1H,s), 6.70-8.05 (8H,m).                                                 12.50 (1H,br)                                                37   1627,   KBr  1.06 (3H,t), 1.75 (2H,six),                                                                   "       20 4 4 2                                   1653         2.30 (3H,s), 2.37 (3H,s)                                                                             100 4 4 2                                                2.90 (2H,t), 3.40 (2H,t),                                                      4.08 (2H,t), 6.30 (1H,s),                                                      6.80-8.00 (9H,m), 12.50 (1H,br)                              38   1610,   KBr  0.66 (3H,t), 0.50-1.80( 4H,m),                                                                "       20 4 4 1                                   1675         2.32 (3H,s), 2.39 (3H,s),                                                                            100 4 4 3                                                3.50 (2H,t), 6.51 (1H,s),                                                      6.80-7.90 (9H,m),                                                              12.25 (1H,br)                                                39   1623,   KBr  2.27 (3H,s), 2.36 (3H,s),                                                                     "       20 4 4 1                                   1667         4.83 (2H,s), 6.57 (1H,s),                                                                            100 4 4 2                                                6.55-7.84 (14H,m),                                                             12.28 (1H,br)                                                40   1623,   KBr  2.27 (3H,s), 2.35 (3H,s),                                                                     "       20 3 4 1                                   1673         4.81 (2H,s), 6.57 (1H,s),                                                                            100 4 4 2                                                6.55-7.85 (13H,m),                                                             12.21 (1H,br)                                                41   1623,   KBr  0.65 (3H,t), 0.40-1.80 (4H,m),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1680         2.41 (3H,t), 3.52 (2H,t),                                                                            100 4 4 1                                                6.50 (1H,t), 6.70-8.17 (9H,m),                                                 12.90 (1H,br)                                                42   1607,   KBr  0.65 (3H,t), 0.40-1.80 (4H,m)                                                                 CDCl.sub.3                                                                             20 4 4 1                                   1680         2.12 (3H,t), 2.21 (3H,t),                                                                     +      100 4 4 1                                                2.43 (3H,t), 3.62 (2H,t),                                                                     DMSO-d.sup.6                                                    6.46 (1H,t), 6.70-7.50 (8H,t),                                                 11.63 (1H,br)                                                43   1605,   KBr  2.20 (6H,t), 2.23 (3H,t),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1617,        4.81 (2H,s), 6.53 (1H,t),                                                                            100 4 4 1                                   1677         6.50-7.60 (13H,m),                                                             12.05 (1H,m)                                                 44   1603,   KBr  2.20 (6H,ms), 2.42 (3H,t),                                                                    "       20 1 2 1                                   1625         2.66 (2H,t), 3.80 (2H,t)                                                                             100 1 3 1                                   1675         6.50 (1H,t), 6.50-7.60 (13H,m),                                                12.00 (1H,br)                                                45   1620,   KBr  0.67 (3H,t), 0.40-1.80 (4H,m),                                                                "       20 3 4 5                                   1675         2.20 (6H,t), 2.40 (3H,t),                                                                            100 3 4 5                                                3.60 (2H,t), 6.49 (1H,t),                                                      6.87-7.20 (8H,m), 11.13 (1H,br)                              46   1625,   KBr  2.10 (6H,s), 2.24 (3H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1650         4.84 (2H,s), 6.60 (1H,s),                                                                            100 4 4 1                                                6.60-7.30 (13H,m),                                                             11.05 (1H,br)                                                47   1630,   KBr  1.06 (3H,t), 1.18 (6H,t),                                                                     "       20 1 2 4                                   1675         0.75-2.10 (4H,m), 2.35 (3H,s),                                                                       100 1 2 4                                                2.63 (4H,q), 3.89 (2H,t),                                                      6.43 (1H,s), 7.25 (3H,s),                                                      8.44 (1H,s), 11.80 (1H,br)                                   48   1630,   Neat 1.20 (6H,t), 0.70-2.00 (10H,m),                                                               "       20 3 3 5                                   1660    Neat 2.40 (3H,s), 2.65 (4H,q),                                                                            100 5 4 5                                                3.35 (2H,q), 3.90 (2H,t),                                                      6.37 (1H,s), 7.03 (3H,s),                                                      11.80 (1H,br)                                                49   1630,   Neat 1.20 (6H,t), 1.33 (3H,t),                                                                     "       20 1 2 3                                   1660         2.27 (3H,s), 2.70 (4H,q),                                                                            100 3 4 5                                                3.30 (2H,q), 5.23 (2H,s),                                                      6.49 (1H,s), 6.80-7.50 (8H,m),                                                 11.81 (1H,br)                                                50   1630,   Neat 1.19 (6H,t), 1.21 (3H,t),                                                                     "       20 5 5 5                                   1650         2.35 (3H,s), 2.66 (4H,q),                                                                            100 5 5 5                                                2.95 (2H,t), 3.37 (2H,q),                                                      4.15 (2H,t), 6.39 (1H,s),                                                      7.00-7.40 (8H,m), 11.70 (1H,br)                              51   1625,   KBr  1.18 (6H,t), 0.80-2.10 (10H,m),                                                               CDCl.sub.3                                                                             20 1 1 3                                   1660         2.37 (3H,s), 2.67 (4H,q),                                                                            100 4 4 4                                                3.30 (H,t), 3.85 (2H,t),                                                       6.39 (1H,s), 7.03 (3H,s),                                                      11.80 (1H,br)                                                52   1627,   Neat 1.17 (6H,t), 0.60-2.00 (12H,m),                                                               "       20 2 3 5                                   1650,        2.37 (3H,s), 2.65 (4H,q),                                                                            100 4 4 5                                   1663         3.20 (2H,t), 3.90 (2H,t),                                                      6.37(1H,s), 7.03 (3H,s),                                                       11.82 (1H,br)                                                53   1630,   KBr  0.95 (3H,t), 1.19 (6H,t),                                                                     "       20 3 4 1                                   1665         1.70 (2H,six), 2.26 (3H,s),                                                                          100 3 4 4                                                2.70 (4H,q), 3.23 (2H,t),                                                      5.18 (2H,s), 6.44 (1H,s),                                                      6.80-7.50 (8H,m), 11.80 (1H,br)                              54   1630,   Neat 1.18 (6H,t), 0.60-2.00 (14H,m),                                                               "       20 2 1 4                                   1665         2.38 (3H,s), 2.65 (4H,q),                                                                            100 4 4 4                                                3.23 (2H,t), 3.92 (2H,t),                                                      6.39 (1H,s), 7.03 (3H,s),                                                      11.78 (1H,br)                                                55   1647    Neat 0.98 (6H,d), 1.17 (6H,t),                                                                     "       20 1 2 4                                                0.50-2.00 (8H,m), 2.39 (3H,s),                                                                       100 5 5 4                                                2.65 (4H,q), 3.22 (2H,d),                                                      3.95 (2H,t), 6.38 (1H,s),                                                      7.02 (3H,s), 12.05 (1H,s),                                   56   1630,   Neat 0.91 (3H,t), 1.10 (6H,t),                                                                     CDCl.sub.3                                                                             20 3 4 5                                   1660         0.70-2.00 (4H,m), 2.36 (3H,s),                                                                       100 5 4 5                                                2.55 (4H,q), 3.80 (2H,t),                                                      4.93 (2H,s), 6.46 (2H,s),                                                      7.00-7.35 (8H,m), 12.70 (1H,br)                              57   1620,   KBr  0.59 (3H,t), 1.10 (6H,t),                                                                     "       20 2 4 4                                   1667         0.50-1.80 (4H,m), 2.43 (3H,s),                                                                       100 4 4 4                                                2.50 (4H,q), 3.62 (2H,t),                                                      6.53 (1H,s), 7.00-7.50 (8H,m),                                                 11.06 (1H,br)                                                58   1623,   KBr                         20 4 4 1                                   1673                               100 4 4 1                              59   1625,   KBr  1.10 (6H,t), 2.29 (3H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1667         2.50 (4H,q), 4.91 (2H,s),                                                                            100 4 4 3                                                6.60 (1H,s), 6.60-7.40 (13H,m),                                                10.98 (1H,br)                                                60   1620,   KBr  1.10 (6H,t), 2.44 (3H,s),                                                                     "       20 1 1 1                                   1660         2.50 (4H,q), 2.67 (2H,t),                                                                            100 1 2 1                                                3.83 (2H,t), 6.50 (1H,s),                                                      6.50-7.40 (13H,m), 11.02 (1H,br)                             61   1600,   KBr  1.10 (6H,t), 1.90 (3H,s),                                                                     CDCl.sub.3                                                                             20 3 4 3                                   1620,        2.02 (3H,s), 2.52 (4H,q),                                                                            100 3 4 4                                   1665         6.59 (1H,s), 6.80-7.10 (12H,m),                                                11.02 (1H,br)                                                62   1620,   KBr                         20 2 3 1                                   1673                               100 3 4 1                              63   1660    Neat 1.18 (6H,t), 0.80- 2.00 (10H,m),                                                              CDCl.sub.3                                                                             20 4 5 5                                                2.65 (4H,q), 2.74 (3H,s),                                                                            100 5 5 5                                                3.32 (2H,q), 4.06 (2H,t),                                                      7.10 (3H,s), 11.20 (1H,br)                                   64   1625,   KBr  1.19 (3H,t), 2.51 (2H,q),                                                                     "       20 4 4 2                                   1660         2.82 (3H,s), 5.16 (2H,s),                                                                            100 4 4 2                                                6.43 (1H,s), 6.70-7.75 (10H,m),                                                12.68 (1H,br)                                                65   1600,   KBr  0.93 (3H,t), 1.65 (2H,six),                                                                   "       20 3 3 1                                   1620,        2.45 (2H,t), 2.87 (3H,s),                                                                            100 3 3 1                                   1673         5.25 (2H,s), 6.40 (1H,s),                                                      6.70-7.75 (10H,m),                                                             12.70 (1H,br)                                                66   1600,   KBr  0.62 (3H,t), 0.50-1.80 (4H,m),                                                                CDCl.sub.3                                                                             20                                         1630,        2.95 (3H,s), 3.85 (2H,t),                                                                            100                                         1665         6.36 (1H,s), 6.90-7.75 (10H,m),                                                12.60 (1H,br)                                                67   1600,   KBr  2.85 (3H,s), 5.09 (2H,s),                                                                     "       20 1 1 1                                   1615,        6.47 (1H,s), 6.64-7.75 (15H,m),                                                                      100 2 1 2                                   1665         12.53 (1H,br)                                                68   1607,   KBr  2.76 (3H,s), 5.30 (2H,s),                                                                     "       20 2 4 1                                   1630,        6.47 (1H,s),          100 3 4 1                                   1680         6.72-7.75 (10H,m),                                                             11.62 (1H,br)                                                69   1620.   KBr  1.19 (6H,t), 0.80-2.00 (10H,m),                                                               "       20 4 4 5                                   1650         2.65 (6H,q), 2.90 (3H,s),                                                                            100 5 5 5                                                3.93 (2H,t), 6.42 (1H,s),                                                      7.06 (3H,s), 11.71 (1H,br)                                   70   1625,   KBr  1.18 (6H,t), 1.22 (3H,t),                                                                     "       20 1 1 4                                   1660         2.55 (2H,q), 2.65 (4H,q),                                                                            100 3 4 4                                                2.79 (3H,s), 5.20 (2H,s),                                                      6.49 (1H,s), 6.80-7.50 (8H,m),                                                 11.80 (1H,br)                                                71   1627,   KBr  1.19 (6H,t), 1.27 (3H,t),                                                                     CDCl.sub.3                                                                             20 4 5 5                                   1650    KBr  2.63 (2H,q), 2.65 (4H,q),                                                                            100 5 5 5                                                2.92 (3H,s), 2.90 (2H,t),                                                      4.18 (2H,t), 6.42 (1H,s),                                                      7.00-7.30 (8H,m), 11.75 (1H,br)                              72   1605,   KBr  1.18 (6H,t), 0.80-2.00 (10H,m),                                                               "       20 1 2 5                                   1650         2.65 (4H,q), 2.84 (3H,s),                                                                            100 4 4 5                                                3.08 (2H,q), 4.00 (2H,t),                                                      7.06 (3H,s), 11.05 (1H,br)                                   73   1615,   KBr  1.16 (6H,t), 1.27 (3H,t),                                                                     "       20 4 5 5                                   1645,        2.65 (4H,q), 2.85 (3H,s),                                                                            100 5 5 5                                   1665         3.00 (2H,t), 3.05 (2H,q),                                                      4.22 (2H,t), 6.95-7.30 (8H,m),                                                 10.89 (1H,br)                                                74   1630,   KBr  1.18 (6H,t), 0.80-2.00 (12H,m)                                                                "       20 2 3 5                                   1660         2.60 (2H,t), 2.65 (4H,q),                                                                            100 5 5 5                                                2.86 (3H,s), 3.90 (2H,t),                                                      6.38 (1H,s), 7.02 (3H,s),                                                      11.72 (1H,br)                                                75   1625,   KBr  1.00 (3H,t), 1.19 (6H,t), 1.20-                                                               "       20 1 1 3                                   1660         1.70 (2H,m), 2.52 (2H,t), 2.63                                                                       100 2 3 4                                                (4H,q), 2.89( 3H,s), 2.95 (2H,t),                                              4.11 (2H,t), 6.38 (1H,s),                                                      6.95-7.30 (8H,m), 11.57 (1H,br)                              76   1630,   KBr  1.18 (6H,t), 2.63 (4H,q),                                                                     CDCl.sub.3                                                                             20 4 4 3                                   1653         2.96 (3H,s), 3.00 (2H,t),                                                                            100 5 5 3                                                4.23 (2H,t), 6.97 (1H,s),                                                      6.95-7.30 (8H,m), 10.88 (1H,br)                              77   1630,   KBr  1.20 (6H,t), 0.80-2.00 (14H,m),                                                               "       20 1 1 3                                   1660         2.60 (2H,t), 2.65 (4H,q),                                                      2.86 (3H,s), 3.93 (2H,t),                                                      6.40 (1H,s), 7.05 (3H,s),                                                      11.73 (1H,br)                                                78   1625,   KBr  1.20 (6H,t), 0.80-1.80 (7H,m),                                                                "       20 1 2 4                                   1660         2.60 (2H,t), 2.67 (4H,q),                                                                            100 2 2 4                                                2.93 (3H,s), 2.97 (2H,t)                                                       4.15 (2H,t), 6.41 (1H,s),                                                      7.00-7.40 (8H,m), 11.61 (1H,br)                              79   1655    KBr  1.17 (6H,t), 0.80-2.00 (7H,m),                                                                "       20 1 2 1                                                2.65 (4H,q), 2.83 (3H,s),                                                                            100 2 2 1                                                3.92 (2H,t), 7.02 (3H,s),                                                      7.10-7.60 (6H,m), 11.57 (1H,br)                              80   1620,   KBr  1.19 (6H,t), 1.70 (4H,m),                                                                     "       20 1 3 4                                   1650         2.62 (4H,m), 2.67 (4H,q),                                                                            100 2 3 4                                                2.93 (3H,s), 2.95 (2H,t),                                                      4.20 (2H,t), 7.00-7.40 (8H,m),                                                 11.72 (1H,br)                                                81   1630,   KBr  2.79 (3H,s), 5.10 (2H,s),                                                                     CDCl.sub.3                                                                             20 1 1 1                                   1650,        6.80-7.70 (16H,m),    100 1 2 1                                   1670         12.60 (1H,br)                                                82                0.80-2.00 (13H,m), 1.28 (3H,s),                                                               "       20 4 4 1                                                2.36 (3H,ms), 3.80 (2H,d),                                                                           100 4 4 1                                                6.35 (1H,s), 6.80-7.80 (5H,m),                                                 12.66 (1H,br)                                                83   1630,   KBr                         20 4 4 1                                   1673                               100 4 4 1                              84                0.70-2.10(18H,m), 2.36 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 2                                                3.78 (2H,d), 6.36 (1H,s),                                                                            100 4 4 2                                                6.80-7.75 (5H,m), 12.57 (1H,br)                              85   1625,   Neat 0.50-2.10 (20H,m), 2.34 (3H,s),                                                               "       20 3 4 1                                   1670         3.75 (2H,d), 6.30 (1H,s),                                                                            100 4 4 1                                                6.80-7.70 (5H,m), 12.60 (1H,br)                              86   1630,   Neat 0.97 (6H,d), 1.70-2.30 (3H,m),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1663         2.25 (3H,s), 2.31 (3H,s),                                                                            100 4 4 1                                                3.50 (2H,d), 5.65 (2H,d),                                                      6.40 (1H,s), 6.70-7.70 (9H,m),                                                 12.45 (1H,br)                                                87   1623,   Neat 0.60-2.30 (14H,m), 0.95 (6H,d),                                                               "       20 4 4 2                                   1663         2.32 (3H,s), 3.82 (2H,d),                                                                            100 4 4 2                                                6.33 (1H,s), 6.80-7.70 (5H,m),                                                 12.38 (1H,br)                                                88   1600,   KBr                         20 4 4 1                                   1645,                              100 3 4 1                                   1667                                                                      89   1630,   KBr                         20 4 4 4                                   1667                               100 4 4 4                              90   1633,   Neat                        20 4 4 1                                   1667                               100 4 4 3                              91   1613,   KBr                         20 4 4 1                                   1627,                              100 4 4 1                                   1667                                                                      92   1633,   Neat 0.70-2.00 (7H,m), 2.22 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1667         2.39 (3H,s), 3.20 (2H,t),                                                                            100 4 4 1                                                5.13 (2H,s), 6.40 (1H,s),                                                      6.70-8.07 (8H,m), 12.47 (1H,br)                              93   1610,   KBr  0.60-2.00 (9H,m), 2.26 (3H,s),                                                                "       20 4 4 1                                   1627,        2.41 (3H,s), 3.26 (2H,t),                                                                            100 4 4 1                                   1657         5.19 (2H,s), 6.41 (1H,s),                                                      6.70-8.05(9H,m), 12.54 (1H,br)                               94   1630,   Neat                        20 1 4 1                                   1670                               100 1 4 1                              95   1633,   KBr  1.37 (3H,t), 2.26 (3H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1675         3.22 (2H,q), 5.13 (2H,s),                                                                            100 4 4 2                                                6.44 (1H,s), 6.70-8.43 (9H,m),                                                 13.22 (1H,br)                                                96                1.00 (3H,t), 1.77 (2H,m),                                                                     CDCl.sub.3                                                                             20 4 4 1                                                2.26 (3H,s), 3.20 (2H,t),                                                                            100 4 4 1                                                5.20 (2H,s), 6.43 (1H,s),                                                      6.70-8.33 (9H,m), 13.18 (1H,br)                              97   1637,   KBr  0.70-2.00 (7H,m), 2.26 (3H,s),                                                                "       20 4 4 1                                   1680         3.18 (2H,t), 5.16 (2H,s),                                                                            100 4 4 1                                                6.39 (1H,s), 6.70-8.40 (9H,m),                                                 13.18 (1H,br)                                                98   1605,   KBr                         20 4 4 1                                   1630,                              100 4 4 3                                   1673                                                                      99   1630,   Neat 2.25 (3H,s), 3.41 (3H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1670         5.01 (2H,s), 5.45 (2H,s),                                                                            100 4 4 1                                                6.50 (1H,s), 6.70-7.77 (10H,m),                                                12.45(1H,br)                                                 100               2.05 (3H,s), 2.30 (3H,s),                                                                     "       20 3 4 1                                                4.83 (2H,d), 6.31 (1H,s),                                                                            100 3 4 1                                                6.60-7.60 (14H,m), 12.50 (1H,br)                             101  1600,   KBr  2.16 (3H,s), 2.25 (3H,s),                                                                     CDCl.sub.3                                                                             20 4 4 1                                   1623,        4.79 (2H,d), 6.53 (1H,s),                                                                            100 4 4 1                                   1670         6.50-7.60 (14H,m),                                                             12.40 (1H,br)                                                102  1627,   KBr  2.32 (3H,s), 4.66 (1H,d),                                                                     "       20 4 4 1                                   1677         5.05 (1H,d), 6.63 (1H,s),                                                                            100 4 4 1                                                6.60-7.60 (14H,m),                                                             12.67 (1H,br)                                                103  1625,   Neat                        20 4 4 1                                   1680                               100 4 4 3                              104  1630,   KBr  0.80-2.00 (7H,m), 1.18 (6H,t),                                                                CDCl.sub.3                                                                             20 5 5 5                                   1657,        2.36 (3H,s), 2.65 (4H,q),                                                                            100 5 5 5                                   1637         3.38 (2H,t), 3.60 (3H,s),                                                      6.42 (1H,s), 7.08 (3H,s),                                                      11.80 (1H,br)                                                105  1667    KBr                         20 4 5 5                                                                      100 4 5 5                              106  1620,   KBr  0.70-2.00 (7H,m), 1.18 (6H,t),                                                                CDCl.sub. 3                                                                            20 4 5 5                                   1655         2.17 (3H,s), 2.30 (3H,s),                                                                            100 5 5 5                                                2.67 (4H,q), 3.40 (2H,t),                                                      3.61 (3H,s), 7.08 (3H,s),                                                      11.85 (1H,br)                                                107  1640,   KBr  0.70-2.00 (7H,m), 1.16 (6H,t),                                                                "       20 5 5 5                                   1667         2.36 (3H,s), 2.61 (4H,q),                                                                            100 5 5 5                                                3.34 (2H,t), 3.57 (3H,s),                                                      6.38 (1H,s), 7.16 (2H,s),                                                      11.99 (1H,br)                                                108  1625,   KBr  0.70-2.00 (7H,m), 1.18 (6H,t),                                                                "       20 5 5 5                                   1660         2.36 (3H,s), 2.62 (4H,q),                                                                            100 5 5 5                                                3.35 (2H,t), 3.57 (3H,s),                                                      7.16 (2H,s), 11.75 (1H,br)                                   109               0.70-2.00 (7H,m), 1.16 (6H,t),                                                                "       20 5 5 5                                                2.16 (3H,s), 2.40 (3H,s),                                                                            100 5 5 5                                                2.63 (4H,q), 3.33 (2H,t)                                                       3.61 (3H,s), 7.16 (2H,s),                                                      12.07 (1H,br)                                                110  1620,   KBr  1.03 (3H,t), 1.20 (6H,t),                                                                     "       20 5 5 5                                   1650         1.73 (2H,m), 2.17 (3H,s),                                                                            100 5 5 5                                                2.40 (3H,s), 2.63 (4H,q),                                                      3.27 (2H,t), 3.62 (3H,s),                                                      7.11 (3H,s), 11.83 (1H,br)                                   111  1625,   KBr  1.17 (6H,t), 0.70-2.00 (5H,m),                                                                CDCl.sub.3                                                                             20 5 5 5                                   1655         2.16 (3H,s), 2.40 (3H,s),                                                                            100 5 5 5                                                2.62 (4H,q), 3.31 (2H,t),                                                      3.61 (3H,s), 7.19 (2H,s),                                                      12.04 (1H,br)                                                112  1620,   KBr  0.70-2.00 (9H,m), 1.18 (6H,t),                                                                "       20 4 4 4                                   1657         2.17 (3H,s), 2.30 (3H,s),                                                                            100 5 4 4                                                2.67 (4H,a), 3.40 (2H,t),                                                      3.61 (3H,s), 7.00 (3H,s),                                                      11.85 (1H,br)                                                113  1630,   KBr  0.60-1.90 (7H,m), 1.89 (3H,s),                                                                "       20 4 4 1                                   1677         4.01 (2H,t), 6.41 (1H,s),                                                                            100 4 4 1                                                6.90-7.70 (9H,m), 12.73 (1H,br)                              114  1600,   KBr                         20 4 4 1                                   1637,                              100 4 5 1                                   1667                                                                      115  1635,   KBr  0.50-1.90 (7H,m), 1.78 (3H,s),                                                                CDCl.sub.3                                                                             20 3 5 1                                   1687         2.95 (2H,t), 6.44 (1H,s),                                                                            100 4 5 1                                                7.00-8.10 (8H,m), 12.60 (1H,br)                              116  1600,   KBr  0.40-2.10 (7H,m), 1.81 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1635,        2.89 (2H,t), 6.41 (1H,s),                                                                            100 4 4 1                                   1680         6.80-8.00 (9H,m), 12.78 (1H,br)                              117  1603,   KBr  0.40-2.00 (7H,m), 1.78 (3H,s),                                                                "       20 4 3 1                                   1640,        .234 (3H,s), 3.00 (2H,t),                                                                            100 4 3 1                                   1670         6.35 (1H,s), 6.70-7.90 (9H,m),                                                 13.11 (1H,br)                                                118  1600,   KBr  0.35-2.00 (7H,m), 1.87 (3H,s),                                                                "       20 1 4 1                                   1635,        3.00 (2H,t), 6.37 (1H,s),                                                                            100 1 4 1                                   1675         6.70-8.00 (9H,m), 12.90 (1H,br)                              119  1600,   KBr  0.40-2.00 (7H,m), 1.85 (3H,s),                                                                "       20 4 4 1                                   1640,        3.03 (2H,t), 6.38 (1H,s),                                                                            100 4 4 1                                   1685         6.75-7.80 (9H,m), 12.82 (1H,br)                              120  1605,   KBr  0.40-2.20 (7H,m), 1.24 (3H,t),                                                                "       20 4 4 1                                   1640,        1.84 (3H,s), 2.69 (2H,q),                                                                            100 4 4 1                                   1675         3.05 (2H,t), 6.39 (1H,s),                                                      6.70-7.85 (9H,m), 13.07 (1H,br)                              121  1600,   KBr  0.50-2.00 (7H,m), 1.88 (3H,s),                                                                CDCl.sub.3                                                                             20 1 4 1                                   1637,        3.00 (2H,t), 6.37 (1H,s),                                                                            100 1 4 1                                   1695         6.75-7.80 (8H,m), 12.72 (1H,br)                              122  1600,   KBr  0.40-2.00 (7H,m), 1.91 (3H,s),                                                                "       20 4 4 1                                   1633,        3.08 (2H,t), 3.82 (3H,s),                                                                            100 4 4 1                                   1673         6.42 (1H,s), 6.60-7.80 (9H,m),                                                 12.90 (1H,br)                                                123  1603,   KBr  0.40-2.00 (7H,m), 2.00-2.70 (1H,                                                              "       20 4 4 1                                   1640,        m), 1.85 (3H,s), 3.10-3.90                                                                           100 4 4 1                                   1675         (1H,m), 6.46 (1H,s), 6.80-7.85                                                 (8H,m), 12.73 (1H,br)                                        124  1600,   KBr  0.50-2.00 (7H,m), 1.85 (3H,s),                                                                "       20 4 4 1                                   1635,        3.00 (2H,t), 6.36 (1H,s),                                                                            100 4 4 1                                   1680         6.70-7.80 (8H,m), 12.75 (1H,br)                              125  1610,   KBr  0.50-1.80 (7H,m), 1.87 (3H,s),                                                                "       20 4 4 1                                   1640,        2.29 (6H,s), 3.03 (2H,t),                                                                            100 4 4 2                                   1673         6.43 (1H,s), 6.40-7.83 (7H,m),                                                 12.40 (1H,br)                                                126  1637,   KBr  0.50-1.90 (7H,m), 1.20 (6H,t),                                                                CDCl.sub.3                                                                             20 1 4 1                                   1660         1.89 (3H,s), 2.70 (4H,q),                                                                            100 1 4 1                                                3.05 (2H,t), 6.45 (1H,s),                                                      7.00-7.55 (7H,m), 12.00 (1H,br)                              127  1633,   KBr  1.12 (6H,t), 2.03 (3H,s),                                                                     "       20 4 4 1                                   1663         2.54 (4H,q), 6.61 (1H,s),                                                                            100 4 4 1                                                6.60-7.50 (12H,m),                                                             11.00 (1H,br)                                                128               0.50-1.93 (7H,m), 1.16 (6H,t),                                                                "       20 1 4 5                                                2.10 (3H,s), 2.62 (4H,q),                                                                            100 4 4 5                                                2.90-3.35 (2H,m), 6.23 (1H,s),                                                 7.06 (3H,s), 11.44 (1H,br),                                                    12.23 (1H,s)                                                 129  1653,   KBr  2.31 (3H,s), 6.23 (1H,s),                                                                     CDCl.sub.3                                                                             20 1 1 1                                   1683         6.80-7.70 (9H,m),                                                                             -DMSO-d.sup.6                                                                         100 1 1 1                                                10.90-12.00 (1H,br),                                                           12.53 (1H,br)                                                130  1633,   KBr  1.03 (3H,t), 1.19 (6H,t),                                                                     CDCl.sub.3                                                                             20 5 5 5                                   1637         1.67 (2H,six), 2.30 (3H,s),                                                                          100 5 5 5                                                2.66 (4H,q), 3.30 (2H,t),                                                      3.49 (3H,s), 6.33 (1H,s),                                                      7.05 (3H,s), 11.90 (1H,br)                                   131  1637,   KBr  1.03 (3H,t), 1.16 (6H,t),                                                                     CDCl.sub.3                                                                             20 5 5 5                                   1663         1.67 (2H,six), 2.32 (3H,s),                                                                          100 5 5 5                                                2.62 (4H,q), 3.30 (2H,t),                                                      3.53 (3H,s), 6.35 (1H,s),                                                      7.16 (2H,s), 12.05 (1H,br)                                   132               1.01 (3H,t), 1.16 (6H,t),                                                                     "       20 5 5 5                                                1.70 (2H,six), 2.34 (3H,s),                                                                          100 5 5 5                                                2.57 (4H,q), 3.30 (2H,t),                                                      3.57 (3H,s), 6.38 (1H,s),                                                      7.35 (2H,s), 12.00 (1H,br)                                   133               1.04 (3H,t), 1.18 (6H,t), 1.70                                                                "       20 5 5 5                                                (2H,six), 2.36 (3H,s), 2.63                                                                          100 5 5 5                                                (4H,q), 3.32 (2H,t), 3.58 (3H,s),                                              3.77 (3H,s), 6.40 (1H,s),                                                      6.64 (2H,s), 11.47 (1H,br)                                   134               1.18 (6H,t), 1.22 (3H,t),                                                                     "       20 4 5 5                                                0.80-2.10 (5H,m), 2.35 (3H,s),                                                                       100 5 5 5                                                2.62 (6H,q), 3.32 (2H,t),                                                      3.56 (3H,s), 6.37 (1H,s),                                                      6.87 (2H,s), 11.60 (1H,br)                                   135  1600,   KBr  2.32 (3H,s), 3.11 (3H,s),                                                                     "       20 1 3 2                                   1633,        6.47 (1H,s), 6.70-7.70 (9H,m),                                                                       100 1 3 5                                   1675         12.75 (1H,br)                                                136  1633,   KBr  1.18 (6H,t), 1.38 (3H,t),                                                                     CDCl.sub.3                                                                             20 5 5 5                                   1667         0.70-2.00 (7h,m), 2.40 (3H,s),                                                                       100 5 5 5                                                2.64 (4H,q), 3.10-3.70 (2H,m),                                                 4.02 (2H,q), 6.41 (1H,s),                                                      7.20 (2H,s), 12.08 (1H,br)                                   137          KBr  1.16 (6H,t), 0.45-2.00 (7H,m),                                                                "       20 1 3 5                                   1657         2.44 (3H,s), 2.63 (4H,q),                                                                            100 1 5 5                                                2.80-3.40 (2H,m), 7.09 (3H,s),                                                 11.75 (2H,br)                                                138  1613,   KBr  1.03 (3H,t), 1.18 (6H,t),                                                                     "       20 5 5 5                                   1660         1.70 (2H,six), 2.70 (3H,s),                                                                          100 5 5 5                                                2.68 (4H,q), 3.28 (2H,t),                                                      3.68 (3H,s), 7.11 (3H,s),                                                      11.07 (1H,br)                                                139  1610,   KBr  1.03 (3H,t), 1.16 (6H,t),                                                                     "       20 5 5 5                                   1660         1.70 (2H,six), 2.62 (4H,q),                                                                          100 5 5 5                                                2.69 (3H,s), 3.27 (2H,t),                                                      3.67 (3H,s), 7.17 (2H,s),                                                      11.27 (1H,br)                                                140  1600,   KBr  1.03 (3H,t), 1.18 (6H,t), 1.23                                                                "       20 4 5 5                                   1667         (3H,t), 1.70 (2H,six), 2.61                                                                          100 5 5 5                                                (2H,q), 2.66 (4H,q), 2.68 (3H,s),                                              3.27 (2H,t), 3.67 (3H,s),                                                      6.93 (2H,s), 10.86 (1H,br)                                   141  1607,   KBr  1.17 (6H,t), 1.43 (3H,t),                                                                     CDCl.sub.3                                                                             20 5 5 5                                   1663         0.60-2.00 (7H,m), 2.63 (4H,q),                                                                       100 5 5 5                                                2.75 (3H,s), 3.00-3.60 (2H,m),                                                 4.14 (2H,q), 7.19 (2H,s),                                                      11.35 (1H,br)                                                142               1.03 (3H,t), 1.18 (6H,t),                                                                     "       20 4 5 5                                                1.23 (3H,t), 1.70 (2H,six),                                                                          100 5 5 5                                                2.17 (3H,s), 2.40 (3H,s),                                                      2.60 (2H,q), 2.65 (4H,q),                                                      3.32 (2H,t), 3.61 (3H,s),                                                      6.91 (2H,s), 11.62 (1H,br)                                   143  1620,   KBr  1.03 (3H,t), 1.16 (6H,t),                                                                     "       20 4 5 5                                   1660         1.70 (2H,six), 2.16 (3H,s),                                                                          100 4 5 5                                                2.40 (3H,s), 2.60 (4H,q),                                                      3.32 (2H,t), 3.62 (3H,s),                                                      7.38 (2H,s), 12.05 (1H,br)                                   144  1617,   KBr  1.17 (6H,t), 1.23 (3H,t),                                                                     "       20 5 5 5                                   1650         0.70-2.20 (7H,m), 2.39 (3H,s),                                                                       100 5 5 5                                                2.63 (4H,q), 2.67 (2H,q),                                                      3.33 (2H,t), 3.61 (3H,s),                                                      7.20 (2H,s), 12.16 (1H,br)                                   145  1633,   Neat 1.03 (3H,t), 1.19 (6H,t),                                                                     "       20 3 5 5                                   1663         1.28 (3H,t), 1.70 (2H,six),                                                                          100 4 5 5                                                2.67 (6H,q), 3.40 (2H,t),                                                      3.59 (3H,s), 6.46 (1H,s),                                                      7.10 (3H,s), 11.82 (1H,br)                                   146  1617,   KBr  1.18 (6H,t), 1.25 (3H,t),                                                                     CDCl.sub.3                                                                             20 3 4 5                                   1667         0.70-2.00 (7H,m), 2.17 (3H,s)                                                                        100 4 5 5                                                2.65 (4H,q), 2.81 (2H,q),                                                      3.10-3.60 (2H,m), 3.67 (3H,s),                                                 7.19 (2H,s), 12.08 (1H,br)                                   147  1625,   KBr  0.40-1.20 (7H,m), 1.83 (3H,s),                                                                "       20 4 4 1                                   1690         3.02 (2H,t), 6.41 (1H,s),                                                                            100 4 4 1                                                6.80-7.90 (10H,m),                                                             13.02 (1H,br)                                                148  1633,   KBr  0.35-2.00 (7H,m), 1.73 (3H,s),                                                                "       20 4 4 1                                   1677         1.93 (3H,s), 2.00-2.50 (1H,m),                                                                       100 4 4 1                                                3.25-3.95 (1H,m), 6.43 (1H,s),                                                 6.70-7.85 (9H,m), 13.13 (1H,br)                              149  1603,   KBr  0.40-2.00 (7H,m), 1.84 (3H,s),                                                                "       20 4 4 1                                   1640,        2.00-3.90 (2H,m), 6.40 (1H,s),                                                                       100 4 4 1                                   1673         6.80-8.00 (9H,m), 12.87 (1H,br)                              150               1.10 (6H,t), 2.24 (3H,s),                                                                     "       20 4 5 5                                                2.41 (3H,s), 2.51 (4H,q),                                                                            100 5 5 5                                                3.23 (3H,s), 6.85-7.55 (8H,m),                                                 11.23 (1H,br)                                                151  1633,   KBr  0.40-2.00 (7H,m), 1.81 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1680,        2.97 (2H,t), 6.43 (1H,s),                                                                            100 4 4 1                                   2280         6.80-8.00 (9H,m), 12.63 (1H,br)                              152  1600,   KBr  0.40-2.00 (7H,m), 1.87 (3H,s),                                                                CDCl.sub.3                                                                             20 4 3 1                                   1637,        2.97 (2H,t), 6.44 (1H,s),                                                                     -DMSO-d.sup.6                                                                         100 4 4 1                                   1680         6.80-8.70 (9H,m), 12.60 (1H,br)                              153  1633,   KBr  0.40-2.00 (7H,m), 1.82 (3H,s),                                                                CDCl.sub.3                                                                             20 1 4 1                                   1685         3.01 (2H,t), 6.37 (1H,s),                                                                            100 1 4 1                                                6.80-7.85 (9H,m), 12.82 (1H,br)                              154  1600,   KBr  0.40-2.00 (7H,m), 1.86 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1633,        2.41 (3H,s), 2.83 (2H,t),                                                                     -DMSO-d.sup.6                                                                         100 4 4 1                                   1675         6.33 (1H,s), 6.80-8.00 (9H,m),                                                 12.56 (1H,br)                                                155  1600,   KBr  0.40-2.00 (7H,m), 1.80 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1637,        2.05 (3H,s), 2.00-2.60 (1H,m),                                                                       100 4 4 1                                   1673         3.25-3.90 (1H,m), 6.46 (1H,s),                                                 6.80-7.80 (8H,m)                                                               12.90 (1H,br)                                                156               0.40-2.00 (7H,m), 1.86 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 1                                                2.45 (3H,s), 3.03 (2H,t),                                                                            100 4 4 1                                                6.40 (1H,s), 6.80-7.85 (8H,s),                                                 12.85 (1H,br)                                                157               0.30-2.50 (7H,m), 1.81 (3H,s),                                                                "       20 4 3 1                                                1.98 (3H,s), 1.90-2.50 (1H,m),                                                                       100 4 3 1                                                3.20-4.10 (1H,m), 6.49 (1H,s),                                                 6.75-7.90 (8H,m), 12.87 (1H,s)                               158               0.40-2.00 (7H,m), 1.79 (3H,s),                                                                "       20 1 4 1                                                2.50-3.40 (2H,m), 6.42 (1H,s),                                                                       100 4 4 1                                                6.80-8.90 (9H,m),                                                              12.70 (1H,s),                                                159  1613,   KBr  0.40-2.00 (7H,m), 1.88 (3H,s),                                                                "       20 4 4 1                                   1637,        2.31 (6H,s), 3.03 (2H,t),                                                                            100 4 4 1                                   1683         6.42 (1H,s), 6.75-7.90 (7H,m),                                                 12.41 (1H,br)                                                160  1605,   KBr  0.40-2.00 (7H,m), 1.88 (3H,s),                                                                "       20 4 4 1                                   1637,        2.29 (6H,s), 2.41 (3H,s),                                                                            100 4 4 2                                   1673         3.05 (2H,t), 6.42 (1H,s),                                                      6.70-7.90 (7H,m), 12.56 (1H,br)                              161  1613,   KBr  0.40-2.00 (7H,m), 1.86 (3H,s),                                                                CDCl.sub.3                                                                             20 4 4 1                                   1640,        2.30 (6H,s), 2.50-3.50 (2H,m),                                                                       100 4 4 2                                   1680         6.44 (1H,s), 6.70-8.00 (7H,m),                                                 12.38 (1H,br)                                                162  1635,   KBr  0.40-2.00 (7H,m), 1.22 (6H,t),                                                                "       20 3 4 2                                   1667         1.91 (3H,s), 2.69 (4H,q),                                                                            100 4 4 2                                                2.50-3.50 (2H,m), 6.47 (1H,s),                                                 6.80-8.00 (7H,m), 11.93 (1H,br)                              163  1633,   KBr  0.40-2.00 (7H,m), 1.19 (3H,s),                                                                "       20 1 2 1                                   1655         1.87 (3H,s), 2.65 (4H,q),                                                                            100 4 5 3                                                2.20-4.10 (2H,m), 6.47 (1H,s),                                                 6.80-7.90 (7H,m), 11.85 (1H,br)                              164               1.03 (3H,t), 1.16 (6H,t),                                                                     "       20 5 5 5                                                1.29 (3H,t), 1.70 (2H,six),                                                                          100 5 5 5                                                2.63 (4H,q), 3.07 (2H,q),                                                      3.27 (2H,t), 3.72 (3H,s),                                                      7.06 (3H,s), 10.95 (1H,br)                                   165               1.04 (3H,t), 1.18 (6H,t),                                                                     "       20 5 5 5                                                1.70 (2H,six), 2.64 (4H,q)                                                                           100 5 5 5                                                2.76 (3H,s), 3.34 (2H,t),                                                      3.68 (3H,s), 3.77 (3H,s),                                                      6.64 (2H,s), 10.64 (1H,br)                                   166               1.01 (3H,t), 1.18 (6H,t),                                                                     CDCl.sub.3                                                                             20 5 5 5                                                1.70 (2H,six), 2.74 (3H,s),                                                                          100 5 5 5                                                2.61 (4H,q), 3.32 (2H,t),                                                      3.76 (3H,s), 7.39 (2H,s),                                                      11.13 (1H,br)                                                __________________________________________________________________________      X: Oryza sativa L.                                                             Y: Echinochloa crusgalli L.                                                    Z: Raphanus sativus L.                                                    

What we claim is:
 1. A compound of the formula: ##STR10## wherein: R is a group -(CH₂)n-R₁ wherein n is an integer from 1 to 3 and R₁ is hydrogen, hydroxy, lower alkoxy, mercapto, lower alkylthio, amino, di-lower alkylamino, C₃₋₁₁ alkyl, lower alkenyl, lower alkynyl, cycloalkyl C₃₋₆ for phenyl substituted by halogen, lower alkyl or lower alkoxy;R₂ and R₇ are different and may each be hydrogen, C₁₋₁₁ alkyl, lower alkenyl, lower alkynyl, C₃₋₆ cycloalkyl, phenyl, or phenyl substituted by halogen, lower alkyl, lower alkoxy, trihalomethyl, nitro or cyano; R₃, R₄ and R₅ are, independently, hydrogen, halogen, cyano, nitro, amino, lower alkyl, lower haloalkyl, hydroxy, lower alkoxy, phenyloxy, carboxy or lower alkoxycarbonyl; R₆ hydrogen, halogen, lower alkyl, phenyl, C₇₋₁₀ aralkyl, or phenyl or C₇₋₁₀ aralkyl substituted by halogen, lower alkyl, lower alkoxy, trihalomethyl, nitro or cyano; and addition salts thereof with acids or bases.
 2. The compound of claim 1, wherein ##STR11## is phenyl, 2-methylphenyl, 2-chlorophenyl, 2,3-dimethylphenyl, 2,6-dimethylphenyl, 2,6-diethylphenyl, 2,6-diethyl-4-substituted (halo, cyano, nitro, amino, lower alkyl, lower haloalkyl, hydroxy, lower alkoxy, phenyloxy, carboxy or lower alkoxy carbonyl) phenyl or 2-ethyl-6-methylphenyl.
 3. The compound of claim 1 wherein ##STR12## is 2-chloro-6-methylphenyl, 3-chloro-2-methylphenyl, 2-ethylphenyl, 2,3-dichlorophenyl, 2,4-dichlorophenyl, 2,5-dichlorophenyl, or 2,6-dichlorophenyl.
 4. The compound of claim 1, wherein the R₂ alkyl, lower alkenyl or lower alkynyl group has from 2 to 5 carbon atoms.
 5. The compound of claim 1, wherein R₆ is methyl or ethyl.
 6. The compound of claim 1, wherein R₇ is methyl or ethyl.
 7. The compound of claim 1, wherein --(CH₂)_(n) --R₁ is methyl, ethyl, propyl, butyl, isobutyl, pentyl, isopentyl or hexyl.
 8. The compound of claim 1, wherein --(CH₂)_(n) --R₁ is 2-methoxyethyl, 2-ethoxyethyl, 3-methoxypropyl or 3-ethoxypropyl.
 9. The compound of claim 1, wherein --(CH₂)_(n) --R₁ is allyl or 2-propynyl.
 10. The compound of claim 1, wherein --(CH₂)_(n) --R₁ is phenylmethyl, substituted phenylmethyl, 2-phenylethyl, 2-(substituted phenyl) ethyl or 3-phenylpropyl.
 11. A plant growth inhibitor composition wherein the active component consists essentially of an effective amount of the compound of claim 1 in admixture with an inert carrier. 